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| Status |
Public on Oct 01, 2022 |
| Title |
Thyroidal gene expression changes in tamoxifen inducible Foxe1 knockout mouse at two weeks post-treatment |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To directly examine the role of Foxe1 in the adult thyroid we generated a model of tamoxifen-inducible Cre mediated Foxe1 deletion in mice of C57BL/6J background (Foxe1flox/flox/Cre). Tamoxifen (0.05g/kg) was administered intraperitoneally to Foxe1flox/flox/Cre mice or Cre control mice aged 6-8 weeks, once daily for five consecutive days. Thyroids were harvested two weeks post-treatment, total RNA extracted and transcriptomic analysis performed using Clariom S Mouse arrays.
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| |
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| Overall design |
Foxe1flox/flox/Cre (n=3) versus Cre control (n=3) mice
|
| Web link |
https://figshare.com/articles/online_resource/Supplementary_docx/19565056
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| |
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| Contributor(s) |
Bullock M |
| Citation(s) |
36156081 |
| Submission date |
Jan 11, 2022 |
| Last update date |
Oct 23, 2022 |
| Contact name |
Martyn Bullock |
| E-mail(s) |
martyn.bullock@sydney.edu.au
|
| Phone |
+61299264768
|
| Organization name |
Univeristy of Sydney
|
| Department |
Kolling Institute
|
| Lab |
Cancer Genetic Laboratory
|
| Street address |
Cnr Reserve Rd and Westbourne St, Royal North Shore Hospital, St Leonards
|
| City |
Sydney |
| State/province |
NSW |
| ZIP/Postal code |
2065 |
| Country |
Australia |
| |
|
| Platforms (1) |
| GPL23038 |
[Clariom_S_Mouse] Affymetrix Clariom S Assay, Mouse (Includes Pico Assay) |
|
| Samples (6)
|
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| Relations |
| BioProject |
PRJNA796233 |
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