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| Status |
Public on Nov 21, 2020 |
| Title |
Targeted single-cell RNA sequencing data of residual TIM-3+ leukemic stem cells post-SCT |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Since AML is hierarchically organized by self-renewing LSCs with heterogeneous sub-populations, we employed single-cell RNA sequencing to evaluate the changes in AML heterogeneity in terms of gene expression profiling, throughout the clinical course.
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| Overall design |
Purified CD34+ BM cells of the diagnostic, CR, and relapse phases, from identical patients, were subjected to BD Rhapsody Single-Cell Analysis System, and the expression of originally customized 435 target genes was quantified
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| Contributor(s) |
Sakoda T, Semba Y |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Nov 20, 2020 |
| Last update date |
Nov 21, 2020 |
| Contact name |
Teppei Sakoda |
| E-mail(s) |
s_teppei@mti.biglobe.ne.jp
|
| Organization name |
Kyushu University
|
| Street address |
3-1-1, Maidashi, Higashi-ku
|
| City |
Fukuoka |
| ZIP/Postal code |
8128582 |
| Country |
Japan |
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| Platforms (1) |
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| Samples (1) |
| GSM4917161 |
BM sample at diagnosis, CR post-SCT and relapse |
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| Relations |
| BioProject |
PRJNA679798 |
| SRA |
SRP293492 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE161894_984_Kyushu_University_Faculty_of_Medicine2_amplicons.fasta.gz |
52.3 Kb |
(ftp)(http) |
FASTA |
| GSE161894_BDAbSeq_Tim3.fasta.gz |
97 b |
(ftp)(http) |
FASTA |
| GSE161894_Sako_rhapsody_SampleTag01_hs_C1Dx_DBEC_MolsPerCell.csv.gz |
167.3 Kb |
(ftp)(http) |
CSV |
| GSE161894_Sako_rhapsody_SampleTag02_hs_C1MRD_DBEC_MolsPerCell.csv.gz |
207.7 Kb |
(ftp)(http) |
CSV |
| GSE161894_Sako_rhapsody_SampleTag03_hs_C1Rel_DBEC_MolsPerCell.csv.gz |
174.3 Kb |
(ftp)(http) |
CSV |
| GSE161894_Sako_rhapsody_SampleTag04_hs_C2Dx_DBEC_MolsPerCell.csv.gz |
188.6 Kb |
(ftp)(http) |
CSV |
| GSE161894_Sako_rhapsody_SampleTag05_hs_C2MRD_DBEC_MolsPerCell.csv.gz |
218.5 Kb |
(ftp)(http) |
CSV |
| GSE161894_Sako_rhapsody_SampleTag06_hs_C2Rel_DBEC_MolsPerCell.csv.gz |
311.3 Kb |
(ftp)(http) |
CSV |
| GSE161894_Samples_and_tag_information.txt.gz |
427 b |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
