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Series GSE1460 Query DataSets for GSE1460
Status Public on Jul 01, 2004
Title Gene Expression Profile during human CD4+ T cell differentiation
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Subpopulations of human fetal thymocyte and circulating naïve T cells were obtained through FACS sorting, including CD3-CD4+CD8- intrathymic T progenitor cells (ITTP), CD3intCD4+CD8+ "double positive" thymocytes (DP), CD3highCD4+CD8- "single positive" thymocytes (SP4), CD3+CD4+CD8-CD45RA+CD62L+ naïve T cells from cord blood (CB4+), and CD3+CD4+CD8-CD45RA+CD62L+ naïve T cells from adult blood (AB4+).
Keywords = Microarray
Keywords = gene expression
Keywords = thymocytes
Keywords = naïve CD4+ T cell
Keywords = recent thymic emigrants
Keywords: other
 
 
Contributor(s) Lee MS, Hanspers K, Barker CS, Korn AP, McCune JM
Citation(s) 15210650
Submission date Jun 07, 2004
Last update date Aug 10, 2018
Contact name Myeong S Lee
E-mail(s) mlee4@itsa.ucsf.edu
Phone (415) 476-5294
Fax (415) 502-8424
Organization name University of California at San Francisco
Department Gladstone Institute of Virology and Immunology
Lab McCune Lab
Street address
City San Francisco
State/province CA
ZIP/Postal code 94143
Country USA
 
Platforms (2)
GPL96 [HG-U133A] Affymetrix Human Genome U133A Array
GPL97 [HG-U133B] Affymetrix Human Genome U133B Array
Samples (30)
GSM24511 ITTP-1A
GSM24609 ITTP-2A
GSM24610 ITTP-3A
Relations
BioProject PRJNA90033

Summary Table header descriptions
Probe Set ID
ACC
Title (Affymetrix)
Gene Symbol
GO Bio Process
GO Cell Component
GO Molecular Function
ITTP-1
ITTP-2
ITTP-3
DP-1
DP-2
SP4-1
SP4-2
SP4-3
CB4-1
CB4-2
AB4-1
AB4-2
AB4-3
TSC-1
TSC-2

Data table
Probe Set ID ACC Title (Affymetrix) Gene Symbol GO Bio Process GO Cell Component GO Molecular Function ITTP-1 ITTP-2 ITTP-3 DP-1 DP-2 SP4-1 SP4-2 SP4-3 CB4-1 CB4-2 AB4-1 AB4-2 AB4-3 TSC-1 TSC-2
1007_s_at U48705 discoidin domain receptor family, member 1 DDR1 GO:7155;cell adhesion;predicted/computed GO:5887;integral to plasma membrane;predicted/computed GO:4714;transmembrane receptor protein tyrosine kinase;predicted/computed 7.933509791 8.091421594 7.645258457 7.963303279 7.972184585 7.849619759 8.094342852 7.961883119 7.758852471 7.805131504 7.967503892 7.808454818 7.438123414 7.640738313 7.776219668
1053_at M87338 replication factor C (activator 1) 2, 40kDa RFC2 GO:5663;DNA replication factor C complex;experimental evidence GO:3687;DNA replication factor;not recorded GO:5524;ATP binding;experimental evidence 6.44785852 6.40392999 6.30274243 5.799075413 5.843113667 5.490496225 5.462663732 5.65298124 5.742867958 5.49008766 5.411787112 5.531962304 5.624960224 5.983254612 5.575090904
117_at X51757 heat shock 70kDa protein 6 (HSP70B') HSPA6 GO:6951;heat shock response;experimental evidence GO:3773;heat shock protein;experimental evidence 5.86149351 6.04054319 6.015725788 5.89363461 5.905827686 5.979633059 6.035927989 6.006994788 6.235467505 6.168744399 6.169146003 6.001849414 6.199683947 5.803221915 5.877265027
121_at X69699 paired box gene 8 PAX8 GO:7275;extended:PAX;Paired box protein, N-terminal GO:development ;1.6e-87;Unknown GO:7397;histogenesis and organogenesis;predicted/computed GO:7345;embryogenesis and morphogenesis;predicted/computed GO:4996;thyroid-stimulating hormone receptor;experimental evidence GO:3700;transcription factor;predicted/computed 8.851032817 9.046203045 8.904479347 8.811141791 8.897142745 8.766644446 9.050473739 9.1061044 8.971364558 9.027281685 9.148207458 9.068358168 8.729317229 8.391684968 8.748768386
1255_g_at L36861 4.71856318 4.686892657 4.837418493 4.736095234 4.692648942 4.671639326 4.829208269 4.724385539 4.736101818 4.738313697 4.755841276 4.777289277 4.710345956 5.180838923 5.015984291
1294_at L13852 ubiquitin-activating enzyme E1-like UBE1L GO:6464;protein modification;not recorded GO:3824;extended:ThiF;UBA/THIF-type NAD/FAD binding fold GO:enzyme ;3.4e-48;Unknown GO:4840;ubiquitin conjugating enzyme;not recorded GO:8047;enzyme activator;not recorded 9.168875759 8.679061598 8.196524325 8.331561722 8.019389769 7.931762559 8.221149915 8.54131586 9.08231938 8.86077316 9.140700989 8.993357875 9.315528582 7.168172965 7.329975423
1316_at X55005 thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) THRA GO:6366;transcription from Pol II promoter;experimental evidence GO:6351;transcription, DNA-dependent;experimental evidence GO:5634;nucleus;not recorded GO:3700;transcription factor;experimental evidence GO:4887;thyroid hormone receptor;experimental evidence 5.030452801 4.949438579 4.971286173 4.903323698 5.017682222 4.959156319 5.116333952 5.071271833 4.87201394 4.939322981 5.147454184 5.131329284 5.060898504 4.713614091 4.723448262
1320_at X79510 protein tyrosine phosphatase, non-receptor type 21 PTPN21 GO:6470;protein amino acid dephosphorylation;predicted/computed GO:157;peripheral plasma membrane protein;predicted/computed GO:5856;cytoskeleton;predicted/computed GO:4725;protein tyrosine phosphatase;predicted/computed 4.479317041 4.58997723 4.479177876 4.580542502 4.595864175 4.424928393 4.580856552 4.686730232 4.779010115 4.644008826 4.699400712 4.584040868 4.613351829 4.509311901 4.657469326
1405_i_at M21121 chemokine (C-C motif) ligand 5 CCL5 GO:7165;signal transduction;experimental evidence GO:6887;exocytosis;experimental evidence GO:7155;cell adhesion;experimental evidence GO:6955;immune response;experimental evidence GO:6979;response to oxidative stress;experimental evidence GO:7267;cell-cell signaling;experimental evidence GO:9615;response to viruses;experimental evidence GO:6968;cellular defense response;experimental evidence GO:6954;inflammatory response;experimental evidence GO:6935;chemotaxis;experimental evidence GO:6874;calcium ion homeostasis;experimental evidence GO:6928;cell motility;experimental evidence GO:8009;chemokine;experimental evidence GO:5102;receptor binding;experimental evidence GO:3800;antiviral response protein;predicted/computed GO:4871;signal transducer;experimental evidence 4.051704592 4.217795615 4.075528986 4.09179216 4.104604931 4.032791057 4.093277932 4.190310601 3.964655084 4.055366724 4.506683216 4.625105896 4.057308614 4.020727513 4.06403982
1431_at J02843 cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 CYP2E1 GO:6118;extended:p450;Cytochrome P450 GO:electron transport ;1e-205;Unknown GO:4497;monooxygenase;experimental evidence GO:15034;cytochrome P450;experimental evidence 4.679527304 4.694892878 4.587185182 4.58449777 4.704659396 4.610437195 4.765072449 4.708244453 4.727468366 4.701695612 4.777655603 4.625014959 4.621199497 4.530386735 4.513104375
1438_at X75208 EphB3 EPHB3 GO:7165;signal transduction;predicted/computed GO:5887;integral to plasma membrane;predicted/computed GO:5003;extended:EPH_lbd;Ephrin receptor, ligand binding GO:ephrin receptor ;1.1e-135;Unknown GO:4714;transmembrane receptor protein tyrosine kinase;predicted/computed 6.206924931 6.382156326 6.414024618 6.180862805 6.252633544 6.190824026 6.460251009 6.519703212 6.825090197 6.726889377 6.654339153 6.596115425 6.419966952 6.241247024 6.652185981
1487_at L38487 estrogen-related receptor alpha ESRRA GO:5634;nucleus;predicted/computed GO:3700;extended:zf-C4;Zn-finger, C4-type steroid receptor GO:transcription factor ;3.1e-51;Unknown GO:3677;DNA binding;predicted/computed GO:4879;ligand-dependent nuclear receptor;predicted/computed 7.065823543 6.862656375 6.770429805 6.950350182 6.937914739 6.898236974 7.156773637 7.060492122 7.442571093 7.201599018 7.155723167 7.167119944 7.12149272 6.985624219 7.002893756
1494_f_at M33318 cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6 CYP2A6 GO:6118;extended:p450;Cytochrome P450 GO:electron transport ;1.5e-192;Unknown GO:5792;microsome;experimental evidence GO:4497;monooxygenase;experimental evidence GO:15034;cytochrome P450;experimental evidence GO:8389;coumarin 7-hydroxylase;experimental evidence 6.565156468 6.788460967 6.615095675 6.579566472 6.681299966 6.483275193 6.744833151 6.744349838 6.7520904 6.64153786 6.75121733 6.81167791 6.50858911 6.415030921 6.502935838
1598_g_at L13720 nucleolar autoantigen (55kD) similar to rat synaptonemal complex protein SC65 GO:7130;synaptonemal complex formation;predicted/computed GO:5730;nucleolus;experimental evidence GO:230;nuclear mitotic chromosome;experimental evidence GO:5716;synaptonemal complex;predicted/computed 8.206580411 8.349258791 8.278609457 8.023120027 8.152939154 7.842008645 8.213257486 8.228836656 8.218079427 8.285095486 8.43964987 8.367496436 8.10892339 9.682740104 9.846594822
160020_at Z48481 matrix metalloproteinase 14 (membrane-inserted) MMP14 GO:6508;proteolysis and peptidolysis;experimental evidence GO:5887;integral to plasma membrane;experimental evidence GO:4222;metalloendopeptidase;experimental evidence GO:8270;zinc binding;predicted/computed 7.335810188 7.391406107 7.335493013 7.326869993 7.57161659 7.32389675 7.447420046 7.511826066 7.373086701 7.586799168 7.585225807 7.392262157 7.261668169 7.410951782 7.187840928
1729_at L41690 TNFRSF1A-associated via death domain TRADD GO:7165;signal transduction;experimental evidence GO:6917;induction of apoptosis;experimental evidence 7.163441777 7.202754992 6.842059955 6.937126177 7.035045576 7.050073039 7.309420932 7.259417581 8.319683029 7.598987193 7.778016998 8.312369815 7.709006792 6.952010542 6.720451208
177_at U38545 phospholipase D1, phophatidylcholine-specific PLD1 GO:7265;RAS protein signal transduction;predicted/computed GO:7264;small GTPase mediated signal transduction;experimental evidence GO:6935;chemotaxis;predicted/computed GO:7242;extended:PX;Phox-like GO:intracellular signaling cascade ;1.2e-25;Unknown GO:6644;phospholipid metabolism;not recorded GO:16020;membrane;experimental evidence GO:4630;phospholipase D;experimental evidence 4.962257165 5.194012918 5.15103418 5.124767874 5.269754277 5.10285457 5.172261658 5.130978666 5.211970846 5.223555752 5.356920771 5.235172671 5.0009097 5.108413257 5.306096081
1773_at L00635 farnesyltransferase, CAAX box, beta FNTB GO:6503;C-terminal protein farnesylation;experimental evidence GO:5737;cytoplasm;not recorded GO:3824;extended:prenyltrans;Prenyltransferase/squalene oxidase GO:enzyme ;4.5e-13;Unknown GO:4660;protein farnesyltransferase;experimental evidence 5.091807357 5.142780748 5.251883931 4.976527511 5.259655199 5.071092007 5.089650674 5.150825977 5.397317086 5.338274457 5.308132825 5.22734458 5.182043198 5.128370191 4.972721624
179_at U38980 postmeiotic segregation increased 2-like 9 PMS2L9 GO:3676;extended:KRAB;KRAB box GO:nucleic acid binding ;1.6e-23;Unknown 8.123794564 8.291325819 8.308290725 8.119927841 8.180126669 7.786155692 8.211174013 8.342130824 8.339527931 8.399545269 8.370872043 8.290056282 8.108941863 7.635962878 7.969237452
1861_at U66879 BCL2-antagonist of cell death BAD GO:8632;apoptotic program;experimental evidence 5.147807565 5.175655529 5.016126585 5.164462286 5.229678648 4.899886085 5.186957176 4.951117437 5.077123141 5.02502899 5.001911403 4.981785568 4.987669344 4.670227993 4.79840522

Total number of rows: 44930

Table truncated, full table size 14472 Kbytes.




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