|
| Status |
Public on Jan 22, 2009 |
| Title |
Expression Profiling of HL-60 Cells Stimulated by ATRA and DMSO |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Stimulation of HL60 progenitor cells with either DMSO (1.25% v/v) or atRA (10E-07M) resulted in their differentiation into neutrophils within six days. Gene expression profiles across 12 600 genes were measured for the differentiation processes induced by DMSO and atRA at 0, 2, 4, 8, 12, and 18 h and daily thereafter until day 7 using oligonucleotide DNA microarrays.
Keywords: time course, differentiation, cell fate transitions
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| |
|
| Overall design |
The experiment consists of 24 Affymetrix hgu95av2 chips. 12 chips were used for the ATRA-stimulated time course, 12 chips were used for the DMSO-stimulated time course.
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| |
|
| Citation(s) |
15903968, 20041215 |
| Submission date |
Jan 21, 2009 |
| Last update date |
Aug 28, 2019 |
| Contact name |
Jessica Mar |
| E-mail(s) |
jess@jimmy.harvard.edu
|
| Phone |
6175828280
|
| Organization name |
Dana-Farber Cancer Institute
|
| Department |
Biostatistics & Computational Biology
|
| Lab |
Quackenbush
|
| Street address |
44 Binney St Smith 822
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL8300 |
[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array |
|
| Samples (25)
|
|
| Relations |
| BioProject |
PRJNA111559 |
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