|
| Status |
Public on Nov 25, 2008 |
| Title |
D. simulans vs. Sechellia bodies choice vs. no choice -Affymetrix |
| Platform organism |
Drosophila melanogaster |
| Sample organisms |
Drosophila sechellia; Drosophila simulans |
| Experiment type |
Expression profiling by array
|
| Summary |
Here we show that Drosophila sechellia—a specialist on the fruit of Morinda citrifolia that recently diverged from its generalist sister-species, D. simulans—has rapidly accumulated loss-of-function alleles and reduced gene expression at genes affecting olfaction, detoxification, and metabolism.
While D. sechellia increases expression of genes involved with oogenesis and fatty acid metabolism when on its host, many more genes show reduced expression in D. sechellia. For several functionally related genes, this decrease in expression is associated with loss-of-function alleles. The rapid accumulation of these alleles potentially affected D. sechellia’s initial adaptation to M. citrifolia, likely contributes to D. sechellia’s poor competitive ability off of its host, and increases ecological isolation between D. sechellia and its sister species.
Keywords: comparative hybridization, gene expression
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| |
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| Overall design |
2 species (simulans and sechella) by choice vs no-choice treatment for octanoic & hexanoic acid blend
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| |
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| Contributor(s) |
Dworkin I, Jones C |
| Citation(s) |
19033155 |
| Submission date |
Nov 24, 2008 |
| Last update date |
Aug 28, 2018 |
| Contact name |
Ian Dworkin |
| Organization name |
Michigan State University
|
| Department |
Zoology
|
| Street address |
203 Natural Science Bldg. Michigan State University
|
| City |
East Lansing |
| State/province |
MI |
| ZIP/Postal code |
48824 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
|
| Samples (8)
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| Relations |
| BioProject |
PRJNA110403 |
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