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| Status |
Public on Sep 30, 2009 |
| Title |
Expression data from kidney of 36d old PKD/Mhm rats. |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Gender has strong impact on kidney performance. Female gender tends to be renal protective. PKD/Mhm is rat model for human polycystic kidney disease (PKD) caused by a mutation in gene Anks6. PKD progresses faster in male rats compared with females.
We used microarrays to detect gender-dependent gene expression in kidney of 36d old PKD/Mhm rats.
Keywords: gender, genotype
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| Overall design |
Gender-dependent gene expression was examined both in heterozygous PKD/Mhm rats affected with PKD and in their wild type littermates. Three microarrays were hybridized for each combination of gender and genotype.
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| Contributor(s) |
Li L, Kerstin F, Andrea B, Bettina K, Priyanka S, Sonja M, Norbert G |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Oct 06, 2008 |
| Last update date |
May 02, 2019 |
| Contact name |
Li Li |
| E-mail(s) |
li.li@gmx.de
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| Organization name |
University Heidelberg
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| Street address |
Theodor-Kutzer-Ufer
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| City |
Mannheim |
| ZIP/Postal code |
68167 |
| Country |
Germany |
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| Platforms (1) |
| GPL341 |
[RAE230A] Affymetrix Rat Expression 230A Array |
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| Samples (12)
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| GSM327250 |
wild type female, biological rep1 |
| GSM327251 |
wild type female, biological rep2 |
| GSM327252 |
wild type female, biological rep3 |
| GSM327253 |
heterozygous affected male, biological rep1 |
| GSM327254 |
heterozygous affected male, biological rep2 |
| GSM327255 |
heterozygous affected male, biological rep3 |
| GSM327256 |
heterozygous affected female, biological rep1 |
| GSM327257 |
heterozygous affected female, biological rep2 |
| GSM327258 |
heterozygous affected female, biological rep3 |
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| Relations |
| BioProject |
PRJNA109983 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE13065_RAW.tar |
29.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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