|
| Status |
Public on Aug 22, 2008 |
| Title |
Expression analysis of growing and senescent activated hepatic stellate cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Cellular senescence is an irreversible proliferative arrest and can be triggered in many cell types in response to diverse forms of cellular damage or stress.
We used microarrays to compare gene expression profile between growing and senescent human activated hepatic stellate cells.
Keywords: cell type comparison
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| |
|
| Overall design |
Two separate preparation of activated hepatic stellate cells were treated with DNA damaging agent to induce senescence or vechicle to remain growing.
RNA was extracted from both replications and used for hybridization on Affymetrix arrays to determine expression differences.
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| |
|
| Contributor(s) |
Krizhanovsky V, Lowe SW |
| Citation(s) |
18724938 |
| Submission date |
Jul 01, 2008 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Valery Krizhanovsky |
| E-mail(s) |
krizh@cshl.edu
|
| Phone |
516-367-8408
|
| Organization name |
Cold Spring harbor Laboratory
|
| Lab |
Lowe lab
|
| Street address |
1 Bungtown Rd
|
| City |
Cold Spring Harbor |
| State/province |
NY |
| ZIP/Postal code |
11724 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA105815 |
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