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| Status |
Public on Jun 01, 2018 |
| Title |
Oncogenic properties of NEAT1 in prostate cancer cells depend on the CDC5L-AGRN transcriptional regulation circuit |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Silencing NEAT1 in prostate cancer cells repressed the transcriptional activity of CDC5L, and RNA-seq and further analyses revealed a handful of potential targets of CDC5L regulated by NEAT1 expression. We have established the requirement of the CDC5L-AGRN circuit for the essential oncogenic role of NEAT1 in prostate cancer cells. Here we provide processed raw counts files.
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| |
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| Overall design |
siNEAT1 and control(siNC) experiments with 2 replicates respectively.
|
| |
|
| Contributor(s) |
Li X, Xiao Z, Huang R, Yang X |
| Citation(s) |
29871935 |
| Submission date |
May 28, 2018 |
| Last update date |
Mar 20, 2019 |
| Contact name |
Xuerui Yang |
| E-mail(s) |
yangxuerui@tsinghua.edu.cn
|
| Organization name |
Tsinghua University
|
| Department |
School of Life Sciences
|
| Street address |
Haidian District
|
| City |
Beijing |
| ZIP/Postal code |
100084 |
| Country |
China |
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| Platforms (1) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA473338 |
| SRA |
SRP149079 |
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