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| Status |
Public on Jun 01, 2018 |
| Title |
Gene expression profiles of human mesenchymal stem cells exposed to surface water organic extracts |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To assess the impact of surface water across the Hun River, several sampling sites located in the mainstream and the tributary were selected representative of pollution gradient and different pollution source. Human mesenchymal stem cells were exposed to organic extracts of surface water from six sites for 2 days.
Microarrays were used to measure the gene expression. And the gene expression profiles were used to evaluate the ability of determine the potential biological effects, to differentiate different pollution source, and to identify the toxic components.
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| Overall design |
The gene expression of human mesenchymal stem cells were measured after 48h exposure to organic extracts of surface water from the Hun River. Culture medium with 0.1% DMSO was used as negative control. Three independent cultures were used for control group and each treatment.
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| Contributor(s) |
Zhang Z, Liu W |
| Citation(s) |
31445443 |
| Submission date |
Feb 07, 2018 |
| Last update date |
Sep 24, 2019 |
| Contact name |
Zhou Zhang |
| E-mail(s) |
andar2008@126.com
|
| Organization name |
Dalian University of Technology
|
| Department |
Environmental Science and Technology
|
| Street address |
Linggong Road 2
|
| City |
Dalian |
| State/province |
Liaoning |
| ZIP/Postal code |
116024 |
| Country |
China |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (21)
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| Relations |
| BioProject |
PRJNA433417 |
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