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Status |
Public on Dec 20, 2017 |
Title |
Expression data from Huh7.5 hepatoma cells transfected with 100 nM miR-7 mimic |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Our work demonstrated that PPAR-α regulates miR-7, a microRNA which regulates SREBP1 signaling. We used microarrays to detail the effect of miR-7 on hepatic gene expression, and, within activated genes, identified an enrichment for genes with SREBP1 binding sites in their promoters.
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Overall design |
Huh7.5 cells were transfected with miR-7 or control mimics (100 nM), and total RNA was isolated 72 hours post-transfection.
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Contributor(s) |
Singaravelu R, Pezacki JP |
Citation(s) |
29321595 |
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Submission date |
Dec 19, 2017 |
Last update date |
Jun 12, 2019 |
Contact name |
John Paul Pezacki |
E-mail(s) |
john.pezacki@uottawa.ca
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Organization name |
University of Ottawa
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Department |
Chemistry and Biomolecular Sciences
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Street address |
150 Louis-Pasteur Pvt
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City |
Ottawa |
State/province |
ON |
ZIP/Postal code |
K1N 6N5 |
Country |
Canada |
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Platforms (1) |
GPL16686 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
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Samples (2) |
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Relations |
BioProject |
PRJNA423013 |