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| Status |
Public on Apr 17, 2019 |
| Title |
Expression data from human neutrophils isolated from the peripheral blood of psoriasis patients and healthy controls |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
In psoriasis, neutrophils accumulate in the epidermis or scatter in the dermis, which may contribute to the inflammation by releasing a variety of cytokines, chemokines, as well as various enzymes and antimicrobe proteins (AMPs). However, the exact role of neutrophils needs to be further illustrated. To identify the differences between psoriasis neutrophils and healthy ones, we analyzed microarray expression data from 3 peripheral neutrophil samples of psoriasis patients and 3 samples of healthy controls. This study identifies that neutrophils are activated and regulated in psoriasis, and these DEGs may contribute to the development of psoriasis.
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| Overall design |
We empolyed CD15 microbeads to isolate peripheral neutrophils of psoriasis patients and healthy controls (n = 3 for each group), and total RNA containing small RNA was extracted
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| Citation missing |
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| Submission date |
Oct 24, 2017 |
| Last update date |
Apr 17, 2019 |
| Contact name |
Shuai Shao |
| E-mail(s) |
857746654@qq.com
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| Organization name |
Xijing Hospital, Fourth Military Medical University
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| Department |
Department of Dermatology
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| Street address |
No. 127 of West Changle Road
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| City |
Xi’an |
| ZIP/Postal code |
710032 |
| Country |
China |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA415584 |
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