Similar studies for GEO DataSets (Select 200025749) - GEO DataSets

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Items: 20

Select item 2000257491.

SAGE libraries from mouse

(Submitter supplied) SAGE libraries from mouse

Organism:: Mus musculus

Type:: Expression profiling by SAGE

Platform:: GPL11
5 Samples

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Series

Accession:: GSE25749

ID:: 200025749

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Select item 2000006082.

Human embryonic stem cells

(Submitter supplied) Undifferentiated human embryonic stem cells grown on mouse embryonic fibroblast feeder layers. HES3 and HES4 are proprietary human ES cell lines of ES Cell International Pte Ltd. Singapore. Keywords: other

Organism:: Homo sapiens

Type:: Expression profiling by SAGE

Platform:: GPL4
2 Samples

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Series

Accession:: GSE608

ID:: 200000608

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Select item 2000036963.

Rat brain microvessel SAGE

(Submitter supplied) SAGE analysis of genes expressed in rat brain microvessels. Keywords: Novel gene identification

Organism:: Rattus norvegicus

Type:: Expression profiling by SAGE

Platform:: GPL23
1 Sample

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Series

Accession:: GSE3696

ID:: 200003696

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Select item 2000003664.

Somatic cells in testes

(Submitter supplied) Gene expression profiles of somatic cells of fetal and adult testis. To identify genes developmentally regulated in the somatic cells of the testis, serial analysis of gene expression (SAGE) has been used to generate gene expression profiles from these cells in the fetal and adult mouse. To avoid germ cell transcripts, a fetal SAGE library was generated from germ cell-free fetal Wv/Wv mice, and an adult SAGE library was generated from adult testes depleted of germ cells with busulfan. more...

Organism:: Mus musculus

Type:: Expression profiling by SAGE

Platform:: GPL11
2 Samples

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Series

Accession:: GSE366

ID:: 200000366

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Select item 2000011515.

CEA_SGF:E00004#TetOFF_Stat3F

(Submitter supplied) The goal of this study was to identify the target genes of Stat3 involved in murine ES cell self-renewal. To achieve this goal, we used the Gs2 ES cell line expressing an inducible dominant negative mutant of Stat3 (Stat3F) in wich Y705 is mutated to phenilalanine. The Gs2 ES cells are routinely maintained in the presence of LIF 1000 U/ml and tetracycline 1µg/ml (LIF/ON). In this condition, Stat3F is not expressed and the cells are maintained in an undifferentiated phenotype. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platforms:: GPL1091 GPL1063
23 Samples

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Series

Accession:: GSE1151

ID:: 200001151

Select item 2000011506.

CEA_SGF:E00005#LIF

(Submitter supplied) In order to identify the genes involved in LIF/gp130 self-renewal response, we analyzed the transcriptome of Gs2 ES cells induced to differentiate upon LIF withdrawal for 16h, 24h and 48h (LIF16, LIF24 and LIF48 respectively)and compared them to that of undifferentiated ES Gs2 cells continuously maintained in the presence of LIF. Since this cell line also carry a tetracycline regulatable dominant negative form of Stat3 (Stat3F, all the experiment was done in the presence of Tetracycline (tet ON) to avoid Stat3F expression. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1091
18 Samples

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Series

Accession:: GSE1150

ID:: 200001150

Select item 1000010917.

CEA_SGF:AFU

(Submitter supplied) Chip contains 9216 features (probes and controls): 2014 PCR products from cDNA matrix using primers specific of genes involved in important biological process (apoptosis, cell cycle, stress response). 1684 PCR products from cDNA clones from the I.M.A.G.E consortium (Research Genetics collection). 2014 PCR products from mouse cDNA clones of a substractive bank (myodistrophic versus normal muscle). 1800 PCR products from rat cDNA clones of a substractive bank (atrophied versus normal muscle). more...

Organism:: Mus musculus

5 Series
107 Samples

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Platform

Accession:: GPL1091

ID:: 100001091

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Select item 2000020268.

Global transcription analysis of immature avian erythrocytic progenitors

(Submitter supplied) The molecular mechanisms regulating the cell fate decision between self-renewal and differentiation/apoptosis in stem and progenitor cells are poorly understood. Here, we report the first comprehensive identification of genes potentially involved in the switch from self-renewal toward differentiation of primary, non-immortalized erythroid avian progenitor cells (T2EC cells). We used the Serial Analysis of Gene Expression (SAGE) technique in order to identify and quantify the genome fraction functionally active in a self-renewing versus a differentiating cell population. more...

Organism:: Gallus gallus

Type:: Expression profiling by SAGE

Platform:: GPL1724
2 Samples

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Series

Accession:: GSE2026

ID:: 200002026

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Select item 2000020429.

Apoptosis and differentiation commitment:novel insights revealed by gene profiling studies in mouse Embryonic Stem cells

(Submitter supplied) Mouse embryonic stem (ES) cells remain pluripotent in vitro when grown in presence of Leukaemia Inhibitory Factor (LIF). LIF starvation leads to apoptosis of some of the ES-derived differentiated cells, together with p38a MAP kinase activation. Apoptosis, but not morphological cell differentiation, is blocked by a p38 inhibitor, PD 169316. To further understand the mechanism of action of this compound, we have identified its specific targets by microarray studies. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Datasets:: GDS1593 GDS1596
Platforms:: GPL81 GPL32
13 Samples

Download data: CEL, EXP

Series

Accession:: GSE2042

ID:: 200002042

Select item 159610.

p38 inhibitor PD169316 effect on embryonic stem derived differentiated cells (U74 Version 2)

Analysis of embryonic stem cells differentiated in the presence of PD169316, an inhibitor of p38 that blocks apoptosis without altering differentiation. Results identify gene families whose transcriptional regulation correlates with cell fate: differentiation with or without apoptosis.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent sets

Platform:: GPL81
Series:: GSE2042
4 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS1596

ID:: 1596

Select item 159311.

p38 inhibitor PD169316 effect on embryonic stem derived differentiated cells (U74A Version 1)

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 cell line sets

Platform:: GPL32
Series:: GSE2042
6 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS1593

ID:: 1593

Select item 20000246912.

CGR8 mouse embryonic stem cells time-course experiment 0 days old vs 3 days old , 0days old vs 10 days old

(Submitter supplied) time-course experiment with embryoid bodies of CGR8 mouse embryonic stem cells ; in the whole time-series RNA from 0 days old embryoid bodies were hybridized against RNA from 3 days and 10 days old embryoid bodies Keywords = embryoid bodies Keywords = mouse Keywords = time-course Keywords = oligonucleotide array Keywords: time-course

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1882
Platform:: GPL1942
4 Samples

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Series

Accession:: GSE2469

ID:: 200002469

Select item 188213.

Embryonic fibroblast-independent embryonic stem cell differentiation

Analysis of CGR8 embryoid bodies differentiating for 3 or 10 days. Culturing of most embryonic stem (ES) cells require embryonic fibroblast (MEF) feeder cells which may affect their gene expression profiles. CGR8 cells are MEF-independent and represent a powerful model of ES cell differentiation.

Organism:: Mus musculus

Type:: Expression profiling by array, log2 ratio, 2 time sets

Platform:: GPL1942
Series:: GSE2469
4 Samples

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DataSet

Accession:: GDS1882

ID:: 1882

Select item 20000049714.

Extraocular muscle, expression changes in critical period (Porter lab)

(Submitter supplied) Evaluation of extraocular muscle (EOM) critical period by expression profiling in dark reared rat. Data form part of publication: Investigative Ophthalmology and Visual Sciences 44: 3842-3855, 2003. Keywords: other

Organism:: Rattus norvegicus

Type:: Expression profiling by SAGE

Platform:: GPL23
2 Samples

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Series

Accession:: GSE497

ID:: 200000497

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Select item 20000168915.

Normal and injured liver sinusoidal endothelial cells

(Submitter supplied) Comparison of C57BL/6J 8-10 weeks male mouse liver sinusoidal endothelial cells (LSEC) from normal liver and from liver injured by carbon tetrachloride administration. Keywords: other

Organism:: Mus musculus

Type:: Expression profiling by SAGE

Platform:: GPL11
2 Samples

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Series

Accession:: GSE1689

ID:: 200001689

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Select item 20000836116.

Juvenile idiopathic arthritis: peripheral blood cells

(Submitter supplied) Systemic-onset juvenile idiopathic arthritis (soJIA) is a rheumatic disease in childhood characterized by systemic symptoms and a relatively poor prognosis. The peripheral leukocytes are thought to play the pathological role of soJIA although the exact cause is still obscure. In this study, we aimed to clarify the cellular functional abnormality in those cells. Here, we analyzed the gene expression profile in peripheral leukocytes from 51 patients with soJIA, 6 patients with poly-articular type JIA (polyJIA) and 8 healthy children utilizing DNA microarrays. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL1291
65 Samples

Download data: TXT

Series

Accession:: GSE8361

ID:: 200008361

Select item 20000131017.

Embryonic stem cell study

(Submitter supplied) Cell culture: H9 hESCs were grown using feeder-free conditions for 7 days after passage then either RNA was harvested or embryoid bodies were prepared, cultured in suspension for 4 days, plated on gelatin-coated plates, and cultured for an additional 9 days in embryoid body medium. Detailed protocols for feeder-free culture and embryoid body formation are available at www.geron.com/scprotocols.pdf RNA preparation: Cells were then harvested in situ by overlaying with RLT lysis buffer (Qiagen, Valencia, CA). more...