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Peterson BS, Trampush J, Maglione M, et al. ADHD Diagnosis and Treatment in Children and Adolescents [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2024 Mar. (Comparative Effectiveness Review, No. 267.)

Cover of ADHD Diagnosis and Treatment in Children and Adolescents

ADHD Diagnosis and Treatment in Children and Adolescents [Internet].

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Appendix AMethods

Search Strategies

Search Strategy KQ1

PubMed

1

“Attention Deficit Disorder with Hyperactivity”[Mesh] OR “attention deficit hyperactivity disorder”[tiab] OR “ADHD”[tiab] OR “attention deficit disorder”[tiab]

2

“Pediatrics”[Mesh] OR “Adolescent”[Mesh] OR “Infant”[Mesh] OR “Child”[Mesh] OR child[tiab] OR children[tiab] OR infant[tiab] OR infants[tiab] OR preschool[tiab] OR preschooler[tiab] OR pediatric [tiab] OR teenager[tiab] OR teenagers[tiab] OR teenaged[tiab] OR teen[tiab] OR teens[tiab] OR adolescent[tiab] OR adolescents[tiab] OR adolescence[tiab] OR youth[tiab] OR paediatric[tiab] OR youths[tiab]

3

“Attention Deficit and Disruptive Behavior Disorders/diagnosis”[Majr] OR mass screening[mesh] OR questionnaires[mesh] OR Interviews as Topic[Mesh] OR Psychometrics[Mesh] OR Psychiatric Status Rating Scales[Mesh] OR diagnosis[mesh:noexp] OR “Diagnostic Techniques and Procedures”[Mesh] OR “Referral and Consultation”[Mesh] OR questionnaire[tiab] OR questionnaires[tiab] OR screening[tiab] OR screen[tiab] OR scale[tiab] OR instrument[tiab] OR instruments[tiab] OR interview[tiab] OR interviews[tiab] OR diagnosis[tiab] OR diagnostic[tiab] OR diagnosed[tiab] OR Measure [tiab] OR test[tiab] OR tests[tiab] OR testing[tiab] OR “Attention Deficit Disorder with Hyperactivity/diagnostic imaging”[Majr]

4

“Sensitivity and Specificity”[Mesh] OR “Diagnostic Errors”[Mesh] OR sensitivity[tiab] OR specificity[tiab] OR (accura*[tiab] AND (diagnos*[tiab] OR classif*[tiab])) OR misdiagnos*[tiab] OR “ROC curve”[tiab] OR “positive predictive value”[tiab] OR “negative predictive value”[tiab] OR “false positive”[tiab] OR “false negative”[tiab] OR “likelihood ratio”[tiab] OR systematic review [tiab]

5

Editorial[ptyp] OR Letter[pt] OR Case Reports[pt] OR Comment[pt] address[pt] OR “autobiography”[pt] OR “bibliography”[pt] OR “biography”[pt] OR “case report”[tw] OR “case reports”[tw] OR “case series”[tw] OR “comment on”[All Fields] OR congress[pt] OR “dictionary”[pt] OR “directory”[pt] OR “festschrift”[pt] OR “historical article”[pt] OR lecture[pt] OR “legal case”[pt] OR “legislation”[pt] OR “news”[pt] OR “newspaper article”[pt] OR “patient education handout”[pt] OR “periodical index”[pt]

6

animals[mh]

7

English[la]

8

#1 AND #2 AND #3 AND #4 NOT #5 NOT #6 AND #7

PUBLICATION DATE RANGE: 2016 to date

PsycINFO (Proquest)

(SU (“Attention Deficit Disorder with Hyperactivity”) OR TI ( “attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder” ) OR AB ( “attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”))

“AND”

(AGE (childhood OR adolescence) OR SU (“Pediatrics”) OR TI (child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth) OR AB (child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth))

“AND”

(SU (“Screening”) OR SU (“Health Screening”) OR SU (“Questionnaires”) OR SU (“Screening Tests”) OR SU (“Psychological Screening Inventory”) OR SU (“Psychiatric Evaluation”) OR SU (“Psychodiagnosis”) OR SU (“Psychodiagnostic Interview”) OR SU (“Psychometrics” OR SU “Rating Scales”) OR SU (“Diagnosis”) OR SU (“Professional Referral”) OR SU (“Diagnostic Interview Schedule”) OR SU (“Behavioral Assessment”) OR TI ( questionnaire OR questionnaires OR screening OR screen OR scale OR instrument OR instruments OR interview OR interviews OR diagnosis OR diagnostic OR diagnosed OR “diagnostic interview schedule for children” OR “diagnostic inventory for screening children”) OR AB (questionnaire OR questionnaires OR screening OR screen OR scale OR instrument OR instruments OR interview OR interviews OR diagnosis OR diagnostic OR diagnosed))

“AND”

SU (“Misdiagnosis”) OR TI (sensitivity OR specificity OR (accura* AND (diagnos* OR classif*)) OR misdiagnos*) OR AB (sensitivity OR specificity OR accuracy OR misdiagnos*)

AND

Record Type: peer reviewed journal

AND

yr(2016-2023)

AND

English language

ERIC (EBSCOhost)

S1

“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”

S2

Screening OR “Health Screening” OR Questionnaires OR “Screening Tests” OR “Psychological Screening Inventory” OR “Psychiatric Evaluation” OR “Psychodiagnosis” OR “Psychodiagnostic Interview” OR “Psychometrics” OR “Rating Scales” OR “Diagnosis” OR “Professional Referral” OR “Diagnostic Interview Schedule” OR “Behavioral Assessment” OR questionnaire OR questionnaires OR screening OR screen OR scale OR instrument OR instruments OR interview OR interviews OR diagnosis OR diagnostic OR diagnosed

S3

“Misdiagnosis” OR sensitivity OR specificity OR (accura* AND (diagnos* OR classif*)) OR misdiagnos*

S4

S1 AND S2 AND S3

Filter:

Publication date range: 2016-2023

EMBASE

#1

‘attention deficit disorder’/exp OR ‘attention deficit disorder’ OR ‘attention deficit hyperactivity disorder’:ab,ti OR ‘adhd’:ab,ti OR ‘attention deficit disorder’:ab,ti

#2

‘pediatrics’/exp OR ‘adolescent’/exp OR ‘infant’/exp OR ‘child’/exp OR child:ab,ti OR children:ab,ti OR infant:ab,ti OR infants:ab,ti OR preschool:ab,ti OR preschooler:ab,ti OR pediatric:ab,ti OR teenager:ab,ti OR teenagers:ab,ti OR teenaged:ab,ti OR teen:ab,ti OR teens:ab,ti OR adolescent:ab,ti OR adolescents:ab,ti OR adolescence:ab,ti OR youth:ab,ti

#3

‘attention deficit disorder’/exp/mj/dm_di OR ‘screening’/exp OR ‘questionnaire’/exp OR ‘interview’/exp OR ‘psychometry’/exp OR ‘psychological rating scale’/exp OR ‘diagnosis’/exp OR ‘assessment of humans’/exp OR ‘checklist’/exp OR ‘clinical assessment tool’/exp OR ‘clinical observation’/exp OR ‘patient referral’/exp OR questionnaire:ab,ti OR questionnaires:ab,ti OR screening:ab,ti OR screen:ab,ti OR scale:ab,ti OR instrument:ab,ti OR instruments:ab,ti OR interview:ab,ti OR interviews:ab,ti OR diagnosis:ab,ti OR diagnostic:ab,ti OR diagnosed:ab,ti

#4

(‘sensitivity and specificity’/exp OR ‘predictive value’/exp OR ‘diagnostic error’/exp OR sensitivity:ab,ti OR specificity:ab,ti OR accuracy:ab,ti OR accurate:ab,ti OR accurately:ab,ti OR misdiagnos*:ab,ti)

NOT (‘case report’/exp OR ‘case study’/exp OR ‘editorial’/exp OR ‘letter’/exp OR ‘note’/exp)

#5

#1 AND #2 AND #3 AND #4

#6

#5 AND [embase]/lim NOT [medline]/lim

#7

#6 AND [humans]/lim AND [2016-2023]/py

Cochrane Reviews

#1

MeSH descriptor: [Attention Deficit Disorder with Hyperactivity] explode all trees

#2

(“attention deficit hyperactivity disorder” OR “ADHD” OR “attention deficit disorder”):ti,ab,kw (Word variations have been searched)

#3

#1 OR #2

#4

MeSH descriptor: [Pediatrics] explode all trees

#5

MeSH descriptor: [Adolescent] explode all trees

#6

MeSH descriptor: [Infant] explode all trees

#7

MeSH descriptor: [Child] explode all trees

#8

#4 OR #5 OR #6 OR #7

#9

#3 OR #8

#10

MeSH descriptor: [Mass Screening] explode all trees

#11

MeSH descriptor: [Surveys and Questionnaires] explode all trees

#12

MeSH descriptor: [Interviews as Topic] explode all trees

#13

MeSH descriptor: [Psychometrics] explode all trees

#14

MeSH descriptor: [Psychiatric Status Rating Scales] explode all trees

#15

MeSH descriptor: [Diagnosis] explode all trees

#16

MeSH descriptor: [Diagnostic Techniques and Procedures] explode all trees

#17

MeSH descriptor: [Referral and Consultation] explode all trees

#18

#1 OR #10 OR #11 OR #12 OR #13 OR #14 OR #15 OR #16 OR #17

#19

(questionnaire OR questionnaires OR screening OR screen OR scale OR instrument OR instruments OR interview OR interviews OR diagnosis OR diagnostic OR diagnosed):ti,ab,kw (Word variations have been searched)

#20

#18 OR #19

#21

#3 AND #9 AND #20

Limited to 2016-2023 and Cochrane Reviews

KQ2

PubMed

1

“Attention Deficit Disorder with Hyperactivity”[Mesh] OR “attention deficit hyperactivity disorder”[tiab] OR “ADHD”[tiab] OR “attention deficit disorder”[tiab]

2

“Pediatrics”[Mesh] OR “Adolescent”[Mesh] OR “Infant”[Mesh] OR “Child”[Mesh] OR child[tiab] OR children[tiab] OR infant[tiab] OR infants[tiab] OR preschool[tiab] OR preschooler[tiab] OR pediatric[tiab] OR teenager[tiab] OR teenagers[tiab] OR teenaged[tiab] OR teen[tiab] OR teens[tiab] OR adolescent[tiab] OR adolescents[tiab] OR adolescence[tiab] OR youth[tiab]

3

(randomized controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR randomised[tiab] OR randomization[tiab] OR randomisation[tiab] OR placebo[tiab] OR randomly[tiab] OR trial[tiab] OR groups[tiab] OR Clinical trial[pt] OR “clinical trial”[tiab] OR “clinical trials”[tiab] OR “evaluation studies”[pt] OR “evaluation studies as topic”[MeSH] OR “evaluation study”[tiab] OR “evaluation studies”[tiab] OR “intervention studies”[MeSH] OR “intervention study”[tiab] OR “intervention studies”[tiab] OR “case-control studies”[MeSH] OR “case-control”[tiab] OR “cohort studies”[MeSH] OR cohort[tiab] OR “longitudinal”[tiab] OR longitudinally[tiab] OR “prospective”[tiab] OR prospectively[tiab] OR “comparative study”[pt] OR “comparative study”[tiab] OR systematic[sb] OR “meta-analysis”[pt] OR “meta-analysis as topic”[MeSH] OR “meta-analysis”[tiab] OR “metaanalyses”[tiab])

4

Editorial[ptyp] OR Letter[pt] OR Case Reports[pt] OR Comment[pt]

5.

animals[mh]

6

English[la]

7

#1 AND #2 AND #3 NOT #4 NOT #5 AND #6

PUBLICATION DATE RANGE: 1980 to date

PsycInfo

S1

(“Attention Deficit Disorder with Hyperactivity”) OR SU “Attention Deficit Disorder with Hyperactivity” OR TI ( “attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder” ) OR AB ( “attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”)

S2

AG (adolescence) OR TI (teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth) OR AB (teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth) OR AG (childhood) OR DE “Pediatrics” OR TI (child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth) OR AB ( child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth)

S3

SU (intervention OR treatment OR therapy OR counseling OR training OR education OR medication OR drug OR psychostimulant OR “Psychotherapy”) OR TI (intervention OR treatment OR therapy OR counseling OR training OR education OR medication OR drug OR psychostimulant OR “Psychotherapy” OR Medicine OR program) OR AB (intervention OR treatment OR therapy OR counseling OR training OR education OR medication OR drug OR psychostimulant OR “Psychotherapy” OR Medicine)

S4

ZC “longitudinal study” OR ZC “empirical study” OR ZC “followup study” OR ZC “longitudinal study” OR ZC “prospective study” OR ZC “systematic review” OR ZC “treatment outcome/clinical trial” OR DE “Clinical Trials” OR DE “Cohort Analysis” OR DE “Followup Studies” OR DE “Longitudinal Studies” OR DE “Prospective Studies” OR TI (randomized OR randomised OR randomization OR randomisation OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR “comparative study”) OR AB (randomized OR randomization OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR “comparative study”)

S5

1 AND 2 AND 3 AND 4

AND

Record Type: peer reviewed journal

AND

yr(2016-2023)

AND

English language

S1

MAINSUBJECT.EXACT(“Attention Deficit Disorder with Hyperactivity”) OR SU “Attention Deficit Disorder with Hyperactivity” OR TI ( “attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder” ) OR AB ( “attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”)

S2

AG (adolescence) OR TI (teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth ) OR AB (teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth )

S3

(MAINSUBJECT.EXACT(“Attention Deficit Disorder with Hyperactivity”) OR SU “Attention Deficit Disorder with Hyperactivity” OR TI (“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”) OR AB (“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”)) AND (AG (adolescence ) OR TI (teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth ) OR AB (teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth ) )

S4

DE “CNS Stimulating Drugs” OR DE “Methylphenidate” OR DE “Dextroamphetamine” OR DE “Amphetamine” OR DE “Clonidine” OR DE “Serotonin Norepinephrine Reuptake Inhibitors” OR DE “Atomoxetine” OR DE “Tricyclic Antidepressant Drugs” OR DE “Desipramine” OR DE “Nortriptyline” OR DE “Bupropion” OR DE “Serotonin Norepinephrine Reuptake Inhibitors” OR DE “Venlafaxine” OR DE “Monoamine Oxidase Inhibitors” OR DE “Amantadine” OR TI ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrine-dopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda) OR AB ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrinedopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda)

S5

DE “Psychotherapy” OR DE “Adolescent Psychotherapy” OR DE “Multisystemic Therapy” OR DE “Behavior Therapy” OR DE “Dialectical Behavior Therapy” OR DE “Brief Psychotherapy” OR DE “Child Psychotherapy” OR DE “Play Therapy” OR DE “Client Centered Therapy” OR DE “Cognitive Behavior Therapy” OR DE “Group Psychotherapy” OR DE “Therapeutic Community” OR DE “Integrative Psychotherapy” OR DE “Psychotherapeutic Counseling” OR DE “Family Therapy” OR DE “Supportive Psychotherapy” OR DE “Cognitive Therapy” OR DE “Parent Training” OR DE “Parent Child Relations” OR DE “Time Management” OR DE “Mindfulness” OR DE “School Based Intervention” OR DE “Memory Training” OR DE “Biofeedback Training” OR DE “Biofeedback” OR DE “Computer Assisted Instruction” OR DE “Intelligent Tutoring Systems” OR DE “Diets” OR DE “Dietary Supplements” OR DE “Food Additives” OR DE “Fatty Acids” OR DE “Acupuncture” OR DE “Remedial Education” OR DE “Early Intervention” OR DE “Alternative Medicine” OR TI (Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR “psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor ) OR AB ( Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR“psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor )

S6

(DE “CNS Stimulating Drugs” OR DE “Methylphenidate” OR DE “Dextroamphetamine” OR DE “Amphetamine” OR DE “Clonidine” OR DE “Serotonin Norepinephrine Reuptake Inhibitors” OR DE “Atomoxetine” OR DE “Tricyclic Antidepressant Drugs” OR DE “Desipramine” OR DE “Nortriptyline” OR DE “Bupropion” OR DE “Serotonin Norepinephrine Reuptake Inhibitors” OR DE “Venlafaxine” OR DE “Monoamine Oxidase Inhibitors” OR DE “Amantadine” OR TI ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrine-dopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda) OR AB ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrinedopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda) ) OR (DE “Psychotherapy” OR DE “Adolescent Psychotherapy” OR DE “Multisystemic Therapy” OR DE “Behavior Therapy” OR DE “Dialectical Behavior Therapy” OR DE “Brief Psychotherapy” OR DE “Child Psychotherapy” OR DE “Play Therapy” OR DE “Client Centered Therapy” OR DE “Cognitive Behavior Therapy” OR DE “Group Psychotherapy” OR DE “Therapeutic Community” OR DE “Integrative Psychotherapy” OR DE “Psychotherapeutic Counseling” OR DE “Family Therapy” OR DE “Supportive Psychotherapy” OR DE “Cognitive Therapy” OR DE “Parent Training” OR DE “Parent Child Relations” OR DE “Time Management” OR DE “Mindfulness” OR DE “School Based Intervention” OR DE “Memory Training” OR DE “Biofeedback Training” OR DE “Biofeedback” OR DE “Computer Assisted Instruction” OR DE “Intelligent Tutoring Systems” OR DE “Diets” OR DE “Dietary Supplements” OR DE “Food Additives” OR DE “Fatty Acids” OR DE “Acupuncture” OR DE “Remedial Education” OR DE “Early Intervention” OR DE “Alternative Medicine” OR TI (Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR “psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor ) OR AB ( Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR“psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor ))

S7

((MAINSUBJECT.EXACT(“Attention Deficit Disorder with Hyperactivity”) OR SU “Attention Deficit Disorder with Hyperactivity” OR TI (“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”) OR AB (“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”)) AND (AG (childhood OR adolescence ) OR DE “Pediatrics” OR TI ( child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth ) OR AB ( child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth ) )) AND ((DE “CNS Stimulating Drugs” OR DE “Methylphenidate” OR DE “Dextroamphetamine” OR DE “Amphetamine” OR DE “Clonidine” OR DE “Serotonin Norepinephrine Reuptake Inhibitors” OR DE “Atomoxetine” OR DE “Tricyclic Antidepressant Drugs” OR DE “Desipramine” OR DE “Nortriptyline” OR DE “Bupropion” OR DE “Serotonin Norepinephrine Reuptake Inhibitors” OR DE “Venlafaxine” OR DE “Monoamine Oxidase Inhibitors” OR DE “Amantadine” OR TI ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrine-dopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda) OR AB ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrinedopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda) ) OR (DE “Psychotherapy” OR DE “Adolescent Psychotherapy” OR DE “Multisystemic Therapy” OR DE “Behavior Therapy” OR DE “Dialectical Behavior Therapy” OR DE “Brief Psychotherapy” OR DE “Child Psychotherapy” OR DE “Play Therapy” OR DE “Client Centered Therapy” OR DE “Cognitive Behavior Therapy” OR DE “Group Psychotherapy” OR DE “Therapeutic Community” OR DE “Integrative Psychotherapy” OR DE “Psychotherapeutic Counseling” OR DE “Family Therapy” OR DE “Supportive Psychotherapy” OR DE “Cognitive Therapy” OR DE “Parent Training” OR DE “Parent Child Relations” OR DE “Time Management” OR DE “Mindfulness” OR DE “School Based Intervention” OR DE “Memory Training” OR DE “Biofeedback Training” OR DE “Biofeedback” OR DE “Computer Assisted Instruction” OR DE “Intelligent Tutoring Systems” OR DE “Diets” OR DE “Dietary Supplements” OR DE “Food Additives” OR DE “Fatty Acids” OR DE “Acupuncture” OR DE “Remedial Education” OR DE “Early Intervention” OR DE “Alternative Medicine” OR TI (Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR “psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor ) OR AB ( Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR“psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor )))

S8

ZC “longitudinal study” OR ZC “empirical study” OR ZC “followup study” OR ZC “longitudinal study” OR ZC “meta analysis” OR ZC “prospective study” OR ZC “retrospective study” OR ZC “systematic review” OR ZC “treatment outcome/clinical trial”OR DE “Clinical Trials” OR DE “Cohort Analysis” OR DE “Followup Studies” OR DE “Longitudinal Studies” OR DE “Prospective Studies” OR DE “Meta Analysis” OR TI (randomized OR randomised OR randomization OR randomisation OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR retrospective OR “comparative study” OR “meta-analysis” OR “meta-analyses” ) OR AB (randomized OR randomised OR randomization OR randomisation OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR retrospective OR “comparative study” OR “meta-analysis” OR “meta-analyses” ) AND (ZZ “journal article”)

S9

(((MAINSUBJECT.EXACT(“Attention Deficit Disorder with Hyperactivity”) OR SU “Attention Deficit Disorder with Hyperactivity” OR TI (“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”) OR AB (“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”)) AND (AG (childhood OR adolescence ) OR DE “Pediatrics” OR TI ( child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth ) OR AB ( child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth ) )) AND ((DE “CNS Stimulating Drugs” OR DE “Methylphenidate” OR DE “Dextroamphetamine” OR DE “Amphetamine” OR DE “Clonidine” OR DE “Serotonin Norepinephrine Reuptake Inhibitors” OR DE “Atomoxetine” OR DE “Tricyclic Antidepressant Drugs” OR DE “Desipramine” OR DE “Nortriptyline” OR DE “Bupropion” OR DE “Serotonin Norepinephrine Reuptake Inhibitors” OR DE “Venlafaxine” OR DE “Monoamine Oxidase Inhibitors” OR DE “Amantadine” OR TI ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrine-dopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda) OR AB ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrinedopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda) ) OR (DE “Psychotherapy” OR DE “Adolescent Psychotherapy” OR DE “Multisystemic Therapy” OR DE “Behavior Therapy” OR DE “Dialectical Behavior Therapy” OR DE “Brief Psychotherapy” OR DE “Child Psychotherapy” OR DE “Play Therapy” OR DE “Client Centered Therapy” OR DE “Cognitive Behavior Therapy” OR DE “Group Psychotherapy” OR DE “Therapeutic Community” OR DE “Integrative Psychotherapy” OR DE “Psychotherapeutic Counseling” OR DE “Family Therapy” OR DE “Supportive Psychotherapy” OR DE “Cognitive Therapy” OR DE “Parent Training” OR DE “Parent Child Relations” OR DE “Time Management” OR DE “Mindfulness” OR DE “School Based Intervention” OR DE “Memory Training” OR DE “Biofeedback Training” OR DE “Biofeedback” OR DE “Computer Assisted Instruction” OR DE “Intelligent Tutoring Systems” OR DE “Diets” OR DE “Dietary Supplements” OR DE “Food Additives” OR DE “Fatty Acids” OR DE “Acupuncture” OR DE “Remedial Education” OR DE “Early Intervention” OR DE “Alternative Medicine” OR TI (Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR “psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor ) OR AB ( Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR“psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor )))) AND (ZC “longitudinal study” OR ZC “empirical study” OR ZC “followup study” OR ZC “longitudinal study” OR ZC “meta analysis” OR ZC “prospective study” OR ZC “retrospective study” OR ZC “systematic review” OR ZC “treatment outcome/clinical trial”OR DE “Clinical Trials” OR DE “Cohort Analysis” OR DE “Followup Studies” OR DE “Longitudinal Studies” OR DE “Prospective Studies” OR DE “Meta Analysis” OR TI (randomized OR randomised OR randomization OR randomisation OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR retrospective OR “comparative study” OR “meta-analysis” OR “meta-analyses” ) OR AB (randomized OR randomised OR randomization OR randomisation OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR retrospective OR “comparative study” OR “meta-analysis” OR “meta-analyses” ) AND (ZZ “journal article”) )

S10

(((MAINSUBJECT.EXACT(“Attention Deficit Disorder with Hyperactivity”) OR SU “Attention Deficit Disorder with Hyperactivity” OR TI (“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”) OR AB (“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”)) AND (AG (childhood OR adolescence ) OR DE “Pediatrics” OR TI ( child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth ) OR AB ( child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth ) )) AND ((DE “CNS Stimulating Drugs” OR DE “Methylphenidate” OR DE “Dextroamphetamine” OR DE “Amphetamine” OR DE “Clonidine” OR DE “Serotonin Norepinephrine Reuptake Inhibitors” OR DE “Atomoxetine” OR DE “Tricyclic Antidepressant Drugs” OR DE “Desipramine” OR DE “Nortriptyline” OR DE “Bupropion” OR DE “Serotonin Norepinephrine Reuptake Inhibitors” OR DE “Venlafaxine” OR DE “Monoamine Oxidase Inhibitors” OR DE “Amantadine” OR TI ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrine-dopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda) OR AB ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrinedopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda) ) OR (DE “Psychotherapy” OR DE “Adolescent Psychotherapy” OR DE “Multisystemic Therapy” OR DE “Behavior Therapy” OR DE “Dialectical Behavior Therapy” OR DE “Brief Psychotherapy” OR DE “Child Psychotherapy” OR DE “Play Therapy” OR DE “Client Centered Therapy” OR DE “Cognitive Behavior Therapy” OR DE “Group Psychotherapy” OR DE “Therapeutic Community” OR DE “Integrative Psychotherapy” OR DE “Psychotherapeutic Counseling” OR DE “Family Therapy” OR DE “Supportive Psychotherapy” OR DE “Cognitive Therapy” OR DE “Parent Training” OR DE “Parent Child Relations” OR DE “Time Management” OR DE “Mindfulness” OR DE “School Based Intervention” OR DE “Memory Training” OR DE “Biofeedback Training” OR DE “Biofeedback” OR DE “Computer Assisted Instruction” OR DE “Intelligent Tutoring Systems” OR DE “Diets” OR DE “Dietary Supplements” OR DE “Food Additives” OR DE “Fatty Acids” OR DE “Acupuncture” OR DE “Remedial Education” OR DE “Early Intervention” OR DE “Alternative Medicine” OR TI (Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR “psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor ) OR AB ( Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR“psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor )))) AND (ZC “longitudinal study” OR ZC “empirical study” OR ZC “followup study” OR ZC “longitudinal study” OR ZC “meta analysis” OR ZC “prospective study” OR ZC “retrospective study” OR ZC “systematic review” OR ZC “treatment outcome/clinical trial”OR DE “Clinical Trials” OR DE “Cohort Analysis” OR DE “Followup Studies” OR DE “Longitudinal Studies” OR DE “Prospective Studies” OR DE “Meta Analysis” OR TI (randomized OR randomised OR randomization OR randomisation OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR retrospective OR “comparative study” OR “meta-analysis” OR “meta-analyses” ) OR AB (randomized OR randomised OR randomization OR randomisation OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR retrospective OR “comparative study” OR “meta-analysis” OR “meta-analyses” ) AND (ZZ “journal article”) ) AND yr(1980-2011)

ERIC

S1

DE “Attention Deficit Hyperactivity Disorder” OR SU “Attention Deficit Hyperactivity Disorder” OR (“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”)

S2

Child OR children OR pediatric OR adolescence OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth

S3

intervention OR treatment OR therapy OR counseling OR training OR education OR medication OR drug OR psychostimulant OR “Psychotherapy” OR Medicine OR program

S4

“longitudinal study” OR “empirical study” OR “followup study” OR “longitudinal study” OR “prospective study” OR “systematic review” OR “treatment outcome/clinical trial” OR “Clinical Trials” OR “Cohort Analysis” OR “Followup Studies” OR “Longitudinal Studies” OR “Prospective Studies” OR randomized OR andomizat OR randomization OR andomization OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR “comparative study”

S5

S1 AND S2 AND S3 AND S4

Publication Date Range: 2016-2023; Publication Type: Scholarly (Peer Reviewed) Journals

S1

DE “Attention Deficit Hyperactivity Disorder” OR SU “Attention Deficit Hyperactivity Disorder” OR (“attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”)

S2

adolescence OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth

S3

S1 AND S2

S4

( “CNS Stimulating Drugs” OR “Methylphenidate” OR “Dextroamphetamine” OR “Amphetamine” OR “Clonidine” OR “Serotonin Norepinephrine Reuptake Inhibitors” OR “Atomoxetine” OR “Tricyclic Antidepressant Drugs” OR “Desipramine” OR “Nortriptyline” OR “Bupropion” OR “Serotonin Norepinephrine Reuptake Inhibitors” OR “Venlafaxine” OR “Monoamine Oxidase Inhibitors” OR “Amantadine” ) OR ( Azstarys OR Cotempla XR-ODT OR Desoxyn OR “Alpha agonist” OR psychostimulants OR “CNS stimulating” OR “Central Nervous System stimulants” OR methylphenidate OR Dexmethylphenidate OR Dextroamphetamine OR lisdexamfetamine OR Amphetamine OR aptensio OR concerta OR Ritalin OR methylin OR medikinet OR equasym OR quillivant OR metadate OR daytrana OR focalin OR Dexedrine OR dextrostat OR procentra OR zenzedi OR Adderall OR vyvanse OR elvanse OR tyvense OR dyanavel OR evekeo OR “alpha-2 agonists” OR guanfacine OR intuniv OR tenex OR estulic OR afken OR clonidine OR catapres OR clophelin OR kapvay OR nexiclon OR duraclon OR “Serotonin Norepinephrine Reuptake Inhibitors” OR Strattera OR atomoxetine OR “Tricyclic Antidepressants “ OR “Desipramine” OR “Nortriptyline” OR norpramin OR pertofrane OR pamelor OR “dopamine reuptake inhibitors” OR modanifil OR Provigil OR alertec OR modavigil OR modiodal OR modalert OR armodafinil OR nuvigil OR “norepinephrine-dopamine reuptake inhibitors” OR bupropion OR Wellbutrin OR zyban OR forfivo OR “Serotonin Norepinephrine Reuptake Inhibitors” OR duloxetine OR Cymbalta OR “serotonin norepinephrine dopamine reuptake inhibitors” OR “Venlafaxine” OR Effexor OR trevilor OR (Monoamine Oxidase AND Inhibitors) OR selegiline OR eldepryl OR emsam OR selgene OR zelapar OR “n methyl d aspartate receptor agonists” OR “Amantadine” OR symmetrel OR memantine OR Namenda )

S5

“Psychotherapy” OR “Adolescent Psychotherapy” OR “Multisystemic Therapy” OR “Behavior Therapy” OR “Dialectical Behavior Therapy” OR “Brief Psychotherapy” OR “Child Psychotherapy” OR “Play Therapy” OR “Client Centered Therapy” OR “Cognitive Behavior Therapy” OR “Group Psychotherapy” OR “Therapeutic Community” OR “Integrative Psychotherapy” OR “Psychotherapeutic Counseling” OR “Family Therapy” OR “Supportive Psychotherapy” OR “Cognitive Therapy” OR “Parent Training” OR “Parent Child Relations” OR “Time Management” OR “Mindfulness” OR “School Based Intervention” OR “Memory Training” OR “Biofeedback Training” OR “Biofeedback” OR “Computer Assisted Instruction” OR “Intelligent Tutoring Systems” OR “Diets” OR “Dietary Supplements” OR “Food Additives” OR “Fatty Acids” OR “Acupuncture” OR “Remedial Education” OR “Early Intervention” OR “Alternative Medicine” OR Monarch external Trigeminal Nerve Stimulation OR eTNS OR “EndeavorRx” OR ((classroom OR school OR schools) AND (behavior intervention OR behavior interventions)) OR “peer intervention” OR ((“organization skills”) AND (training OR intervention)) OR “psychosocial therapy” OR “psychosocial intervention” OR “psychosocial interventions” OR “psychosocial approach” OR “psychosocial approaches” OR “psychosocial treatment” OR “psychosocial support” OR “psychoeducation” OR “nonpharmacologic therapy” OR “nondrug therapy” OR “non-drug therapy” OR “Play Therapy” OR “cognitive behavioral therapy” OR “cognitive behavior therapy” OR “cognitive behavioural therapy” OR “cognitive behaviour therapy” OR Mindfulness OR complementary OR “alternative medicine” OR “alternative therapy” OR “alternative therapies” OR “Interpersonal skills training” OR “Parent-Child Interaction Therapy” OR “parent training” OR “parent engagement” OR “parent management” OR “parenting skills” OR “parenting intervention” OR “parenting interventions” OR “Barkley’s defiant child” OR “Teacher-Child Interaction Training” OR “Incredible Years” OR “New Forest Parenting” OR “Triple P” OR “Helping the Noncompliant Child” OR “child life and attention skills” OR “clas” OR PCIT OR “parent child interaction therapy” OR “Summer Treatment Program” OR “Daily Report Card” OR “organization skills” OR “organizational skills” OR “time management” OR “homework intervention” OR braintrain OR “memory training” OR “Captain’s log mindpower builder” OR “memory gyms” OR “attention gym” OR “smartdriver plus” OR “smartmind pro” OR “RoboMemo” OR “play attention” OR metronome OR brainmaster OR mindmed OR “attention lab” OR (activate AND c8) OR “attention training” OR “CogniPlus” OR cogmed OR “working memory training” OR biofeedback OR neurofeedback OR neuroagility OR neuroptimal OR acupuncture OR “vision training” OR “visual training” OR “vision therapy” OR “education intervention” OR “cognitive remediation” OR neurotherapy OR “elimination diet” OR “diet therapy” OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates” OR “gluten free”) AND diet) OR “feingold diet” OR “red dye” OR ((vitamin OR vitamins) AND (supplement OR supplements)) OR “herbal supplement” OR “herbal supplements” OR probiotics OR “omega 3” OR “slow cortical potentials” OR “few foods diet” OR “oligoantigenic diet” OR “restriction diet” OR “food intolerance” OR “food allergy” OR “food allergies” OR “food sensitivity” OR “food sensitivities” OR “multimodal treatment” OR homeopathy OR homeopathic OR chiropractic OR chiropractor

S6

S4 OR S5

S7

S3 AND S6

S8

“longitudinal study” OR “empirical study” OR “followup study” OR “longitudinal study” OR “meta analysis” OR “prospective study” OR “retrospective study” OR “systematic review” OR “treatment outcome/clinical trial” OR “Clinical Trials” OR “Cohort Analysis” OR “Followup Studies” OR “Longitudinal Studies” OR “Prospective Studies” OR “Meta Analysis” OR randomized OR randomised OR randomization OR randomisation OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR retrospective OR “comparative study” OR “meta-analysis” OR “meta-analyses”

S9 S7 AND S8

Publication Date Range: 1980-2011; Publication Type: Journal Articles

EMBASE

1

‘attention deficit disorder’/exp OR ‘attention deficit disorder’ OR ‘attention deficit hyperactivity disorder’:ab,ti OR ‘adhd’:ab,ti OR ‘attention deficit disorder’:ab,ti

2

‘child’/exp OR ‘pediatric’/exp OR ‘adolescent’/exp

OR child:ab,ti OR children:ab,ti OR pediatrics:ab,ti OR teenager:ab,ti OR teenagers:ab,ti OR teenaged:ab,ti OR teen:ab,ti OR teens:ab,ti OR adolescent:ab,ti OR adolescents:ab,ti OR adolescence:ab,ti OR youth:ab,ti

3

#1 AND #2

4

‘intervention’:ab,ti OR ‘treatment’:ab,ti OR ‘therapy’:ab,ti OR ‘counseling’:ab,ti OR ‘training’:ab,ti OR ‘education’:ab,ti OR ‘medication’:ab,ti OR ‘drug’:ab,ti OR ‘psychostimulant’:ab,ti OR ‘Psychotherapy’:ab,ti OR ‘Medicine’:ab,ti OR ‘program’:ab,ti

5

#3 AND #4

6

(‘randomized controlled trial’/exp OR ‘crossover procedure’/exp OR ‘double blind procedure’/exp OR ‘single blind procedure’/exp OR random*:ab,ti OR factorial*:ab,ti OR crossover*:ab,ti OR ((cross NEAR/1 over*):ab,ti) OR placebo*:ab,ti OR ((doubl* NEAR/1 blind*):ab,ti) OR ((singl* NEAR/1 blind*):ab,ti) OR assign*:ab,ti OR allocat*:ab,ti OR volunteer*:ab,ti OR ‘clinical study’/exp OR ‘clinical trial’:ti,ab OR ‘clinical trials’:ti,ab OR ‘controlled study’/exp OR ‘evaluation’/exp OR ‘evaluation study’:ab,ti OR ‘evaluation studies’:ab,ti OR ‘intervention study’:ab,ti OR ‘intervention studies’:ab,ti OR ‘case control’:ab,ti OR ‘cohort analysis’/exp OR cohort:ab,ti OR longitudinal*:ab,ti OR prospective:ab,ti OR prospectively:ab,ti OR ‘follow up’/exp OR ‘follow up’:ab,ti OR ‘comparative effectiveness’/exp OR ‘comparative study’/exp OR ‘comparative study’:ab,ti OR ‘comparative studies’:ab,ti OR ‘evidence based medicine’/exp OR ‘systematic review’:ab,ti) NOT (‘case report’/exp OR ‘case study’/exp OR ‘editorial’/exp OR ‘letter’/exp OR ‘note’/exp)

7

#5 AND #6

8

#7 AND [embase]/lim NOT [medline]/lim

9

#8 AND [humans]/lim AND [2016-2023]/py

1

‘attention deficit disorder’/exp OR ‘attention deficit disorder’ OR ‘attention deficit hyperactivity disorder’:ab,ti OR ‘adhd’:ab,ti OR ‘attention deficit disorder’:ab,ti

2

‘adolescent’/exp OR teenager:ab,ti OR teenagers:ab,ti OR teenaged:ab,ti OR teen:ab,ti OR teens:ab,ti OR adolescent:ab,ti OR adolescents:ab,ti OR adolescence:ab,ti OR youth:ab,ti

3

#1 AND #2

4

‘azstarys’:ab,ti OR ‘cotempla xr-odt’:ab,ti OR ‘desoxyn’:ab,ti OR ‘alpha agonist’:ab,ti OR ‘attention deficit disorder’/exp/mj/dm_dt OR ‘central stimulant agent’/exp OR ‘psychostimulant agent’/exp OR ‘guanfacine’/exp OR ‘adrenergic receptor affecting agent’/exp OR ‘atomoxetine’/exp OR ‘antidepressant agent’/exp OR ‘n methyl dextro aspartic acid receptor’/exp OR ‘memantine’/exp OR ‘amantadine’/exp OR ‘dopamine uptake inhibitor’/exp OR ‘central nervous system stimulants’:ab,ti OR ‘psychostimulant’:ab,ti OR ‘methylphenidate’:ab,ti OR ‘methylphenidate hydrochloride’:ab,ti OR ‘aptensio’:ab,ti OR ‘concerta’:ab,ti OR ‘ritalin’:ab,ti OR ‘ritalin la’:ab,ti OR ‘medikinet’:ab,ti OR ‘equasym’:ab,ti OR ‘quillivant’:ab,ti OR ‘metadate’:ab,ti OR ‘daytrana’:ab,ti OR ‘dexmethylphenidate’:ab,ti OR ‘dexmethylphenidate hydrochloride’:ab,ti OR ‘focalin’:ab,ti OR ‘dextroamphetamine’:ab,ti OR ‘dexedrine’:ab,ti OR ‘dextrostat’:ab,ti OR ‘procentra’:ab,ti OR ‘zenzedi’:ab,ti OR ‘mixed amphetamine salts’:ab,ti OR ‘adderall’:ab,ti OR ‘lisdexamfetamine’:ab,ti OR ‘lisdexamfetamine dimesylate’:ab,ti OR ‘vyvanse’:ab,ti OR ‘venvanse’:ab,ti OR ‘elvanse’:ab,ti OR ‘tyvense’:ab,ti OR ‘dyanavel’:ab,ti OR ‘evekeo’:ab,ti OR ‘guanfacine’:ab,ti OR ‘sympatholytics’:ab,ti OR ‘central alpha-2 adrenergic agonist’:ab,ti OR ‘clonidine’:ab,ti OR ‘intuniv’:ab,ti OR ‘estulic’:ab,ti OR ‘tenex’:ab,ti OR ‘catapres’:ab,ti OR ‘clophelin’:ab,ti OR ‘kapvay’:ab,ti OR ‘nexiclon’:ab,ti OR ‘duraclon’:ab,ti OR ‘norepinephrine reuptake inhibitors’:ab,ti OR ‘selective norepinephrine reuptake inhibitors’:ab,ti OR ‘adrenergic uptake inhibitors’:ab,ti OR ‘atomoxetine’:ab,ti OR ‘strattera’:ab,ti OR ‘tricyclic antidepressants’:ab,ti OR ‘desipramine’:ab,ti OR ‘norpramin’:ab,ti OR ‘nortriptyline’:ab,ti OR ‘pamelor’:ab,ti OR ‘dopamine reuptake inhibitors’:ab,ti OR ‘modafinil’:ab,ti OR ‘provigil’:ab,ti OR ‘armodafinil’:ab,ti OR ‘norepinephrine-dopamine reuptake inhibitors’:ab,ti OR ‘bupropion’:ab,ti OR ‘wellbutrin’:ab,ti OR ‘forfivo’:ab,ti OR ‘venlafaxine’:ab,ti OR ‘reboxetine’:ab,ti OR ‘monoamine oxidase type b inhibitors’:ab,ti OR ‘selegiline’:ab,ti OR ‘nmda receptors’:ab,ti OR ‘n-methyl-d-aspartate receptor antagonists’:ab,ti OR ‘amantadine’:ab,ti OR ‘memantine’:ab,ti OR ‘pertofrane’:ab,ti OR ‘nuvigil’:ab,ti OR ‘cymbalta’:ab,ti OR ‘duloxetine’:ab,ti OR ‘effexor’:ab,ti OR ‘eldepryl’:ab,ti OR ‘emsam’:ab,ti OR ‘trevilor’:ab,ti OR ‘symmetrel’:ab,ti OR ‘namenda’:ab,ti OR ‘zelapar’:ab,ti

5

‘monarch external trigeminal nerve stimulation’:ab,ti OR etns:ab,ti OR ((classroom:ab,ti OR school:ab,ti OR schools:ab,ti) AND (‘behavior intervention’:ab,ti OR ‘behavior interventions’:ab,ti)) OR ‘peer intervention’:ab,ti OR (‘organization skills’:ab,ti AND (training:ab,ti OR intervention:ab,ti)) OR ‘attention deficit disorder’/exp/mj/dm_rh,dm_dm OR ‘psychotherapy’/exp OR ‘child psychiatry’/exp OR ‘child parent relation’/exp OR ‘time management’/exp OR ‘feedback system’/exp OR ‘teaching’/exp OR ‘adaptive behavior’/exp OR ‘diet therapy’/exp OR ‘omega 3 fatty acid’/exp OR ‘vitamin’/exp/dd_do,dd_dt,dd_ad OR ‘food additive’/exp/dd_ae OR ‘probiotic agent’/exp OR ‘acupuncture’/exp OR ‘early childhood intervention’/exp OR ‘alternative medicine’/exp OR ‘psychosocial therapy’:ab,ti OR ‘psychosocial intervention’:ab,ti OR ‘psychosocial interventions’:ab,ti OR ‘psychosocial approach’:ab,ti OR ‘psychosocial approaches’:ab,ti OR ‘psychosocial treatment’:ab,ti OR ‘psychosocial support’:ab,ti OR ‘psychoeducation’:ab,ti OR ‘nonpharmacologic therapy’:ab,ti OR ‘nondrug therapy’:ab,ti OR ‘non-drug therapy’:ab,ti OR ‘play therapy’:ab,ti OR ‘cognitive behavioral therapy’:ab,ti OR ‘cognitive behavior therapy’:ab,ti OR ‘cognitive behavioural therapy’:ab,ti OR ‘cognitive behaviour therapy’:ab,ti OR mindfulness:ab,ti OR complementary:ab,ti OR ‘alternative medicine’:ab,ti OR ‘alternative therapy’:ab,ti OR ‘alternative therapies’:ab,ti OR ‘interpersonal skills training’:ab,ti OR ‘parent-child interaction therapy’:ab,ti OR ‘parent training’:ab,ti OR ‘parent engagement’:ab,ti OR ‘parent management’:ab,ti OR ‘parenting skills’:ab,ti OR ‘parenting intervention’:ab,ti OR ‘parenting interventions’:ab,ti OR ‘barkleys defiant child’:ab,ti OR ‘teacher-child interaction training’:ab,ti OR ‘incredible years’:ab,ti OR ‘new forest parenting’:ab,ti OR ‘triple p’:ab,ti OR ‘helping the noncompliant child’:ab,ti OR ‘child life and attention skills’:ab,ti OR ‘clas’:ab,ti OR pcit:ab,ti OR ‘parent child interaction therapy’:ab,ti OR ‘summer treatment program’:ab,ti OR ‘daily report card’:ab,ti OR ‘organization skills’:ab,ti OR ‘organizational skills’:ab,ti OR ‘time management’:ab,ti OR ‘homework intervention’:ab,ti OR braintrain:ab,ti OR ‘memory training’:ab,ti OR ‘captains log mindpower builder’:ab,ti OR ‘memory gyms’:ab,ti OR ‘attention gym’:ab,ti OR ‘smartdriver plus’:ab,ti OR ‘smartmind pro’:ab,ti OR ‘robomemo’:ab,ti OR ‘play attention’:ab,ti OR metronome:ab,ti OR brainmaster:ab,ti OR mindmed:ab,ti OR ‘attention lab’:ab,ti OR (activate:ab,ti AND c8:ab,ti) OR ‘attention training’:ab,ti OR ‘cogniplus’:ab,ti OR cogmed:ab,ti OR ‘working memory training’:ab,ti OR biofeedback:ab,ti OR neurofeedback:ab,ti OR neuroagility:ab,ti OR neuroptimal:ab,ti OR acupuncture:ab,ti OR ‘vision training’:ab,ti OR ‘visual training’:ab,ti OR ‘vision therapy’:ab,ti OR ‘education intervention’:ab,ti OR ‘cognitive remediation’:ab,ti OR neurotherapy:ab,ti OR ‘elimination diet’:ab,ti OR ‘diet therapy’:ab,ti OR ((‘low carb’ OR ‘low carbohydrate’ OR ‘low carbohydrates’:ab,ti OR ‘gluten free’) AND diet:ab,ti) OR ‘feingold diet’:ab,ti OR ‘red dye’:ab,ti OR ((vitamin:ab,ti OR vitamins:ab,ti) AND (supplement:ab,ti OR supplements:ab,ti)) OR ‘herbal supplement’:ab,ti OR ‘herbal supplements’:ab,ti OR probiotics:ab,ti OR ‘omega 3’:ab,ti OR ‘slow cortical potentials’:ab,ti OR ‘few foods diet’:ab,ti OR ‘oligoantigenic diet’:ab,ti OR ‘restriction diet’:ab,ti OR ‘food intolerance’:ab,ti OR ‘food allergy’:ab,ti OR ‘food allergies’:ab,ti OR ‘food sensitivity’:ab,ti OR ‘food sensitivities’:ab,ti OR ‘multimodal treatment’:ab,ti OR homeopathy:ab,ti OR homeopathic:ab,ti OR chiropractic:ab,ti OR chiropractor:ab,ti

6

#4 OR #5

7

#3 AND #6

8

(‘randomized controlled trial’/exp OR ‘crossover procedure’/exp OR ‘double blind procedure’/exp OR ‘single blind procedure’/exp OR random*:ab,ti OR factorial*:ab,ti OR crossover*:ab,ti OR ((cross NEAR/1 over*):ab,ti) OR placebo*:ab,ti OR ((doubl* NEAR/1 blind*):ab,ti) OR ((singl* NEAR/1 blind*):ab,ti) OR assign*:ab,ti OR allocat*:ab,ti OR volunteer*:ab,ti OR ‘clinical study’/exp OR ‘clinical trial’:ti,ab OR ‘clinical trials’:ti,ab OR ‘controlled study’/exp OR ‘evaluation’/exp OR ‘evaluation study’:ab,ti OR ‘evaluation studies’:ab,ti OR ‘intervention study’:ab,ti OR ‘intervention studies’:ab,ti OR ‘case control’:ab,ti OR ‘cohort analysis’/exp OR cohort:ab,ti OR longitudinal*:ab,ti OR prospective:ab,ti OR prospectively:ab,ti OR retrospective:ab,ti OR ‘follow up’/exp OR ‘follow up’:ab,ti OR ‘comparative effectiveness’/exp OR ‘comparative study’/exp OR ‘comparative study’:ab,ti OR ‘comparative studies’:ab,ti OR ‘evidence based medicine’/exp OR ‘systematic review’:ab,ti OR ‘meta-analysis’:ab,ti OR ‘meta-analyses’:ab,ti) NOT (‘case report’/exp OR ‘case study’/exp OR ‘editorial’/exp OR ‘letter’/exp OR ‘note’/exp)

9

#7 AND #8

10

#9 AND [embase]/lim NOT [medline]/lim

11

#10 AND [humans]/lim AND [1980-2011]/py

Cochrane Reviews

#1

[mh “Attention Deficit Disorder with Hyperactivity”] OR attention deficit hyperactivity disorder:ab,ti OR “ADHD”:ab,ti OR “attention deficit disorder”:ab,ti

#2

[mh Adolescent] OR Child:ab,ti OR children:ab,ti OR pediatric:abti OR teenager:ab,ti OR teenagers:ab,ti OR teenaged:ab,ti OR teen:ab,ti OR teens:ab,ti OR adolescent:ab,ti OR adolescents:ab,ti OR adolescence:ab,ti OR youth:ab,ti

#3

[mh “Attention Deficit Disorder with Hyperactivity”/DT] OR ‘intervention’:ab,ti OR ‘treatment’:ab,ti OR ‘therapy’:ab,ti OR ‘counseling’:ab,ti OR ‘training’:ab,ti OR ‘education’:ab,ti OR ‘medication’:ab,ti OR ‘drug’:ab,ti OR ‘psychostimulant’:ab,ti OR ‘Psychotherapy’:ab,ti OR ‘Medicine’:ab,ti OR ‘program’:ab,ti

#4

#1 AND #2 AND #3

Limited to 2016-2023 and Cochrane Reviews

#1

[mh “Attention Deficit Disorder with Hyperactivity”]

#2

attention deficit hyperactivity disorder:ab,ti OR “ADHD”:ab,ti OR “attention deficit disorder”:ab,ti

#3

#1 OR #2

#4

[mh Adolescent]

#5

teenager:ab,ti OR teenagers:ab,ti OR teenaged:ab,ti OR teen:ab,ti OR teens:ab,ti OR adolescent:ab,ti OR adolescents:ab,ti OR adolescence:ab,ti OR youth:ab,ti

#6

#4 OR #5

#7

[mh “Attention Deficit Disorder with Hyperactivity”/DT] OR [mh “Central Nervous System Stimulants”] OR [mh Methylphenidate] OR [mh Dexmethylphenidate] OR [mh Dextroamphetamine] OR [mh Amphetamine] OR [mh Guanfacine] OR [mh Sympatholytics] OR [mh Clonidine] OR [mh “Adrenergic Uptake Inhibitors”] OR [mh “alpha-2 Adrenergic Receptors”] OR [mh “Adrenergic alpha-Agonists”] OR [mh “Adrenergic alpha-2 Receptor Agonists”] OR [mh “Tricyclic Antidepressive Agents”] OR [mh Desipramine] OR [mh “Dopamine Uptake Inhibitors”] OR [mh Sympathomimetics] OR [mh “Serotonin Uptake Inhibitors”] OR [mh “Monoamine Oxidase Inhibitors”] OR [mh “Monoamine Oxidase”] OR [mh Selegiline] OR [mh Bupropion] OR [mh “N-Methyl-D-Aspartate Receptors”] OR [mh Memantine] OR [mh Amantadine]

#8

“Azstarys”:ab,ti OR “Cotempla XR-ODT”:ab,ti OR “Desoxyn”:ab,ti OR “Alpha agonist”:ab,ti OR “psychostimulants”:ab,ti OR “CNS stimulating”:ab,ti OR “Central Nervous System Stimulants”:ab,ti OR “psychostimulant”:ab,ti OR “Methylphenidate”:ab,ti OR “Methylphenidate Hydrochloride”:ab,ti OR “Aptensio”:ab,ti OR “Concerta”:ab,ti OR “Ritalin”:ab,ti OR “Ritalin LA”:ab,ti OR “Medikinet”:ab,ti OR “Equasym”:ab,ti OR “Quillivant”:ab,ti OR “Metadate”:ab,ti OR “Daytrana”:ab,ti OR “Dexmethylphenidate”:ab,ti OR “Dexmethylphenidate Hydrochloride”:ab,ti OR “Focalin”:ab,ti OR “Dextroamphetamine”:ab,ti OR “Dexedrine”:ab,ti OR “Dextrostat”:ab,ti OR “ProCentra”:ab,ti OR “Zenzedi”:ab,ti OR “mixed amphetamine salts”:ab,ti OR “Adderall”:ab,ti OR “lisdexamfetamine”:ab,ti OR “lisdexamfetamine dimesylate”:ab,ti OR “Vyvanse”:ab,ti OR “Venvanse”:ab,ti OR “Elvanse”:ab,ti OR “Tyvense”:ab,ti OR “Dyanavel”:ab,ti OR “Evekeo”:ab,ti OR “Guanfacine”:ab,ti OR “Sympatholytics”:ab,ti OR “Central alpha-2 Adrenergic Agonist”:ab,ti OR “Clonidine”:ab,ti OR “Intuniv”:ab,ti OR “Estulic”:ab,ti OR “Tenex”:ab,ti OR “Catapres”:ab,ti OR “Clophelin”:ab,ti OR “Kapvay”:ab,ti OR “Nexiclon”:ab,ti OR “Duraclon”:ab,ti OR “Norepinephrine Reuptake Inhibitors”:ab,ti OR “Selective Norepinephrine Reuptake Inhibitors”:ab,ti OR Adrenergic Uptake Inhibitors:ab,ti OR “atomoxetine”:ab,ti OR “Strattera”:ab,ti OR “Tricyclic antidepressants”:ab,ti OR “Desipramine”:ab,ti OR “Norpramin”:ab,ti OR “Nortriptyline”:ab,ti OR “Pamelor”:ab,ti OR Dopamine Reuptake Inhibitors:ab,ti OR “modafinil”:ab,ti OR “Provigil”:ab,ti OR Armodafinil:ab,ti OR Norepinephrine-dopamine Reuptake Inhibitors:ab,ti OR “Bupropion”:ab,ti OR “Wellbutrin”:ab,ti OR “Forfivo”:ab,ti OR “Cymbalta”:ab,ti OR “venlafaxine”:ab,ti OR “reboxetine”:ab,ti OR Monoamine Oxidase Type B inhibitors:ab,ti OR “Selegiline”:ab,ti OR “Eldepryl”:ab,ti OR “Zelapar”:ab,ti OR “NMDA receptors”:ab,ti OR N-Methyl-D-aspartate receptor Antagonists:ab,ti OR “Amantadine”:ab,ti OR “Memantine”:ab,ti OR “Pertofrane”:ab,ti OR “Nuvigil”:ab,ti OR “Cymbalta”:ab,ti OR “duloxetine”:ab,ti OR “Effexor”:ab,ti OR “Eldepryl”:ab,ti OR “Emsam”:ab,ti OR “Trevilor”:ab,ti OR “Symmetrel”:ab,ti OR “Namenda”:ab,ti OR “Zelapar”:ab,ti

#9

#7 OR #8

#10

‘monarch external trigeminal nerve stimulation’:ab,ti OR etns:ab,ti OR ((classroom:ab,ti OR school:ab,ti OR schools:ab,ti) AND (‘behavior intervention’:ab,ti OR ‘behavior interventions’:ab,ti)) OR ‘peer intervention’:ab,ti OR (‘organization skills’:ab,ti AND (training:ab,ti OR intervention:ab,ti)) OR [mh “Attention Deficit Disorder with Hyperactivity”/DH] OR [mh “Attention Deficit Disorder with Hyperactivity”/RH] OR [mh Psychotherapy] OR [mh “Behavior Therapy”] OR [mh “Parent-Child Relations”] OR [mh “Play Therapy”] OR [mh “Cognitive Therapy”] OR [mh “Time Management”] OR [mh “Computer-Assisted Instruction”] OR [mh “Diet Therapy”] OR [mh “Omega-3 Fatty Acids”/TU] OR [mh Vitamins/AD] OR [mh Vitamins/TU] OR [mh “Food Additives”/AE] OR [mh Probiotics/TU] OR [mh “Acupuncture Therapy”] OR [mh “Remedial Teaching”] OR [mh “Early Intervention (Education)”] OR [mh “Complementary Therapies”] OR [mh “Combined Modality Therapy”]

#11

psychosocial therapy:ab,ti OR “psychosocial intervention”:ab,ti OR “psychosocial interventions”:ab,ti OR “psychosocial approach”:ab,ti OR “psychosocial approaches”:ab,ti OR “psychosocial treatment”:ab,ti OR “psychosocial support”:ab,ti OR “psychoeducation”:ab,ti OR “nonpharmacologic therapy”:ab,ti OR “nondrug therapy”:ab,ti OR “non-drug therapy”:ab,ti OR “Play Therapy”:ab,ti OR “cognitive behavioral therapy”:ab,ti OR “cognitive behavior therapy”:ab,ti OR “cognitive behavioural therapy”:ab,ti OR “cognitive behaviour therapy”:ab,ti OR Mindfulness:ab,ti OR complementary:ab,ti OR “alternative medicine”:ab,ti OR “alternative therapy”:ab,ti OR “alternative therapies”:ab,ti OR “Interpersonal skills training”:ab,ti OR “Parent-Child Interaction Therapy”:ab,ti OR “parent training”:ab,ti OR “parent engagement”:ab,ti OR “parent management”:ab,ti OR “parenting skills”:ab,ti OR “parenting intervention”:ab,ti OR “parenting interventions”:ab,ti OR “Barkley’s defiant child”:ab,ti OR “TeacherChild Interaction Training”:ab,ti OR “Incredible Years”:ab,ti OR “New Forest Parenting”:ab,ti OR “Triple P”:ab,ti OR “Helping the Noncompliant Child”:ab,ti OR “child life and attention skills”:ab,ti OR “clas”:ab,ti OR PCIT:ab,ti OR “parent child interaction therapy”:ab,ti OR “Summer Treatment Program”:ab,ti OR “Daily Report Card”:ab,ti OR “organization skills”:ab,ti OR “organizational skills”:ab,ti OR “time management”:ab,ti OR “homework intervention”:ab,ti OR braintrain:ab,ti OR “memory training”:ab,ti OR “Captain’s log mindpower builder”:ab,ti OR “memory gyms”:ab,ti OR “attention gym”:ab,ti OR “smartdriver plus”:ab,ti OR “smartmind pro”:ab,ti OR “RoboMemo”:ab,ti OR “play attention”:ab,ti OR metronome:ab,ti OR brainmaster:ab,ti OR mindmed:ab,ti OR “attention lab”:ab,ti OR (activate:ab,ti AND c8:ab,ti) OR “attention training”:ab,ti OR “CogniPlus”:ab,ti OR cogmed:ab,ti OR “working memory training”:ab,ti OR biofeedback:ab,ti OR neurofeedback:ab,ti OR neuroagility:ab,ti OR neuroptimal:ab,ti OR acupuncture:ab,ti OR “vision training”:ab,ti OR “visual training”:ab,ti OR “vision therapy”:ab,ti OR “education intervention”:ab,ti OR “cognitive remediation”:ab,ti OR neurotherapy:ab,ti OR “elimination diet”:ab,ti OR “diet therapy”:ab,ti OR ((“low carb” OR “low carbohydrate” OR “low carbohydrates”:ab,ti OR “gluten free”) AND diet:ab,ti) OR “feingold diet”:ab,ti OR “red dye”:ab,ti OR ((vitamin:ab,ti OR vitamins:ab,ti) AND (supplement:ab,ti OR supplements:ab,ti)) OR “herbal supplement”:ab,ti OR “herbal supplements”:ab,ti OR probiotics:ab,ti OR “omega 3”:ab,ti OR “slow cortical potentials”:ab,ti OR “few foods diet”:ab,ti OR “oligoantigenic diet”:ab,ti OR “restriction diet”:ab,ti OR “food intolerance”:ab,ti OR “food allergy”:ab,ti OR “food allergies”:ab,ti OR “food sensitivity”:ab,ti OR “food sensitivities”:ab,ti OR “multimodal treatment”:ab,ti OR homeopathy:ab,ti OR homeopathic:ab,ti OR chiropractic:ab,ti OR chiropractor:ab,ti

#12

#10 OR #11

#13

#12 OR #9

#14

#3 AND #6 AND #13

with Cochrane Library publication date Between Jan 1980 and Dec 2011, in Cochrane Reviews

#15

#3 AND #6

in Cochrane Reviews

KQ3

PubMed

1

“Attention Deficit Disorder with Hyperactivity”[Mesh] OR “attention deficit hyperactivity disorder”[tiab] OR “ADHD”[tiab] OR “attention deficit disorder”[tiab]

2

“Pediatrics”[Mesh] OR “Adolescent”[Mesh] OR “Infant”[Mesh] OR “Child”[Mesh] OR child[tiab] OR children[tiab] OR infant[tiab] OR infants[tiab] OR preschool[tiab] OR preschooler[tiab] OR pediatric[tiab] OR teenager[tiab] OR teenagers[tiab] OR teenaged[tiab] OR teen[tiab] OR teens[tiab] OR adolescent[tiab] OR adolescents[tiab] OR adolescence[tiab] OR youth[tiab]

3

monitor[tiab] OR monitored[tiab] OR monitoring[tiab] OR “follow up”[tiab] OR “followed up”[tiab] OR visit[tiab] OR visits[tiab] OR session[tiab] OR sessions[tiab] OR appointment[tiab] OR appointments[tiab]

4

(randomized controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR randomised[tiab] OR randomization[tiab] OR randomisation[tiab] OR placebo[tiab] OR randomly[tiab] OR trial[tiab] OR groups[tiab] OR Clinical trial[pt] OR “clinical trial”[tiab] OR “clinical trials”[tiab] OR “evaluation studies”[pt] OR “evaluation studies as topic”[MeSH] OR “evaluation study”[tiab] OR “evaluation studies”[tiab] OR “intervention studies”[MeSH] OR “intervention study”[tiab] OR “intervention studies”[tiab] OR “case-control studies”[MeSH] OR “case-control”[tiab] OR “cohort studies”[MeSH] OR cohort[tiab] OR “longitudinal”[tiab] OR longitudinally[tiab] OR “prospective”[tiab] OR prospectively[tiab] OR “retrospective”[tiab] OR “comparative study”[pt] OR “comparative study”[tiab] OR systematic[sb] OR “meta-analysis”[pt] OR “meta-analysis as topic”[MeSH])

5

Editorial[ptyp] OR Letter[pt] OR Case Reports[pt] OR Comment[pt]

6

animals[mh]

7

humans[mh]

8

English[la]

9

#1 AND #2 AND #3 AND #4 NOT #5 NOT #6 NOT #7 AND #8

Publication Date Range: 1980 to date

PsycINFO

#1

SU “Attention Deficit Disorder with Hyperactivity” OR TI ( “attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder” ) OR AB ( “attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”)

#2

AGE (childhood OR adolescence ) OR SU “Pediatrics” OR TI ( child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth ) OR AB ( child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth )

#3

TI(monitor OR monitored OR monitoring OR (“follow up” OR “followed up” OR visit OR visits OR session OR sessions OR appointment OR appointments) AND (schedule* OR strategy*) OR “longitudinal” OR longitudinally OR “long term”) OR AB(monitor OR monitored OR monitoring OR (“follow up” OR “followed up” OR visit OR visits OR session OR sessions OR appointment OR appointments) AND (schedule* OR strategy*) OR “longitudinal” OR longitudinally OR “long term”)

#4

“longitudinal study” OR “empirical study” OR “followup study” OR “longitudinal study” OR “meta analysis” OR “prospective study” OR “retrospective study” OR “systematic review” OR “treatment outcome/clinical trial”OR “Clinical Trials” OR “Cohort Analysis” OR “Followup Studies” OR “Longitudinal Studies” OR “Prospective Studies” OR “Meta Analysis” OR TI (randomized OR randomised OR randomization OR randomisation OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR retrospective OR “comparative study” OR “meta-analysis” OR “meta-analyses” ) OR AB (randomized OR randomised OR randomization OR randomisation OR randomly OR trial OR groups OR trials OR “evaluation study” OR evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR retrospective OR “comparative study” OR “meta-analysis” OR “meta-analyses” )

#5

#1 AND #2 AND #3 AND #4

AND

Record Type: peer reviewed journal

AND

yr(1980-2023)

AND

English language

ERIC

#1

“Attention Deficit Disorder with Hyperactivity” OR TI/AB “attention deficit hyperactivity disorder” OR ADHD OR “attention deficit disorder”

#2

childhood OR adolescence OR “Pediatrics” OR TI/AB ( child OR children OR infant OR infants OR preschool OR preschooler OR pediatric OR teenager OR teenagers OR teenaged OR teen OR teens OR adolescent OR adolescents OR adolescence OR youth )

#3

TI/AB monitor OR monitored OR monitoring OR ((“follow up” OR “followed up” OR visit OR visits OR session OR sessions OR appointment OR appointments) AND (schedule* OR strategy*)) OR longitudinal OR longitudinally OR “long term”

#4

“longitudinal study” OR “empirical study” OR “followup study” OR “longitudinal study” OR “meta analysis” OR “prospective study” OR “retrospective study” OR “systematic review” OR “treatment outcome/clinical trial” OR “Clinical Trials” OR “Cohort Analysis” OR “Followup Studies” OR “Longitudinal Studies” OR “Prospective Studies” OR “Meta Analysis” OR TI/AB (randomized OR llocate t OR randomization OR llocate tion OR randomly OR trial OR groups OR trials OR “evaluation study” OR

evaluation studies OR “intervention study” OR “intervention studies” OR “case-control” OR cohort OR longitudinal OR longitudinally OR prospective OR prospectively OR retrospective OR “comparative study” OR “meta-analysis” OR “meta-analyses” )

#5

#1 AND #2 AND #3 AND #4

Publication Date Range: 1980-2023; Publication Type: Scholarly (Peer Reviewed) Journals

EMBASE

#1

‘attention deficit disorder’/exp OR “attention deficit hyperactivity disorder”:ab,ti OR “ADHD”:ab,ti OR “attention deficit disorder”:ab,ti

#2

‘pediatrics’/exp OR ‘adolescent’/exp OR ‘infant’/exp OR ‘child’/exp OR child:ab,ti OR children:ab,ti OR infant:ab,ti OR infants:ab,ti OR preschool:ab,ti OR preschooler:ab,ti OR pediatric:ab,ti OR teenager:ab,ti OR teenagers:ab,ti OR teenaged:ab,ti OR teen:ab,ti OR teens:ab,ti OR adolescent:ab,ti OR adolescents:ab,ti OR adolescence:ab,ti OR youth:ab,ti

#3

monitor:ab,ti OR monitored:ab,ti OR monitoring:ab,ti OR ((‘follow up’:ab,ti OR ‘followed up’:ab,ti OR visit:ab,ti OR visits:ab,ti OR session:ab,ti OR sessions:ab,ti OR appointment:ab,ti OR appointments:ab,ti) AND (schedule* OR strategy*)) OR ‘longitudinal’:ab,ti OR longitudinally:ab,ti OR ‘long term’:ab,ti

#4

(‘randomized controlled trial’/exp OR ‘crossover procedure’/exp OR ‘double blind procedure’/exp OR ‘single blind procedure’/exp OR random*:ab,ti OR factorial*:ab,ti OR crossover*:ab,ti OR (cross NEAR/1 over*):ab,ti OR placebo*:ab,ti OR (doubl* NEAR/1 blind*):ab,ti OR (singl* NEAR/1 blind*):ab,ti OR assign*:ab,ti OR llocate*:ab,ti OR volunteer*:ab,ti OR ‘clinical study’/exp OR ‘clinical trial’:ti,ab OR ‘clinical trials’:ti,ab OR ‘controlled study’/exp OR ‘evaluation’/exp OR ‘evaluation study’:ab,ti OR ‘evaluation studies’:ab,ti OR ‘intervention study’:ab,ti OR ‘intervention studies’:ab,ti OR ‘case control’:ab,ti OR ‘cohort analysis’/exp OR cohort:ab,ti OR longitudinal*:ab,ti OR prospective:ab,ti OR prospectively:ab,ti OR retrospective:ab,ti OR ‘follow up’/exp OR ‘follow up’:ab,ti OR ‘comparative effectiveness’/exp OR ‘comparative study’/exp OR ‘comparative study’:ab,ti OR ‘comparative studies’:ab,ti OR ‘evidence based medicine’/exp OR ‘systematic review’:ab,ti OR ‘meta-analysis’:ab,ti OR ‘meta-analyses’:ab,ti) NOT (‘case report’/exp OR ‘case study’/exp OR ‘editorial’/exp OR ‘letter’/exp OR ‘note’/exp)

#5

#1 AND #2 AND #3 AND #4

#6

#5 AND [embase]/lim NOT [medline]/lim

#7

#6 AND [humans]/lim AND [1980-2023]/py

Cochrane Reviews

#1

[mh “Attention Deficit Disorder with Hyperactivity”]

#2

attention deficit hyperactivity disorder:ab,ti OR ADHD:ab,ti OR attention deficit disorder:ab,ti

#3

#1 OR #2

#4

[mh Pediatrics] OR [mh Adolescent] OR [mh Infant] OR [mh Child]

#5

child:ab,ti OR children:ab,ti OR infant:ab,ti OR infants:ab,ti OR preschool:ab,ti OR preschooler:ab,ti OR pediatric:ab,ti OR teenager:ab,ti OR teenagers:ab,ti OR teenaged:ab,ti OR teen:ab,ti OR teens:ab,ti OR adolescent:ab,ti OR adolescents:ab,ti OR adolescence:ab,ti OR youth:ab,ti

#6

#4 OR #5

#7

monitor:ab,ti OR monitored:ab,ti OR monitoring:ab,ti OR ((“follow up”:ab,ti OR “followed up”:ab,ti OR visit:ab,ti OR visits:ab,ti OR session:ab,ti OR sessions:ab,ti OR appointment:ab,ti OR appointments:ab,ti) AND (schedule* OR strategy*)) OR longitudinal:ab,ti OR longitudinally:ab,ti OR “long term”:ab,ti

#8

#6 OR #7

#9

#3 AND #6 AND #8

Limited to 1980-2023 and Cochrane Reviews

ClinicalTrials.gov

Conditions: ADHD OR attention deficit

Recruitment: Completed studies

Study Results: All studies

Study type: Interventional studies

Age group: Child

Phase: Phase 2, Phase 3, Phase 4

2016-2023

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