Table 18KQ2 summary of findings and strength of evidence for neurostimulation

KQ2 Intervention and ComparisonOutcomeNumber of Studies; Study Design and IDsFindingsReasons for DowngradingSoE
KQ2 neurostimulation vs controlBehavior0 studiesNo dataCInsufficient
KQ2 neurostimulation vs controlBroadband measures1 RCT517No systematic effect (SMD 0.19; CI −0.60, 0.97, 1 study, n=25)S, CInsufficient
KQ2 neurostimulation vs controlADHD symptoms1 RCT517No systematic effect (SMD −0.58; CI −1.39, 0.22; 1 study, n=25)S, CInsufficient
KQ2 neurostimulation vs controlFunctional impairment0 studiesNo dataCInsufficient
KQ2 neurostimulation vs controlAcceptability of treatment0 studiesNo dataCInsufficient
KQ2 neurostimulation vs controlAcademic performance0 studiesNo dataCInsufficient
KQ2 neurostimulation vs controlAppetite suppression0 studiesNo dataCInsufficient
KQ2 neurostimulation vs controlParticipants with adverse events0 studiesNo dataCInsufficient

Notes: ADHD = attention deficit hyperactivity disorder, C = inconsistency, CI = 95% confidence interval, I = imprecision, KQ = Key Question, RCT = randomized controlled trial, S = study limitation, SMD = standardized mean differences, SoE = strength of evidence

From: 5, Results: Treatment of ADHD

Cover of ADHD Diagnosis and Treatment in Children and Adolescents
ADHD Diagnosis and Treatment in Children and Adolescents [Internet].
Comparative Effectiveness Review, No. 267.
Peterson BS, Trampush J, Maglione M, et al.
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