Table D.4, Applicability for included studies, KQ2 - ADHD Diagnosis and Treatment in Children and Adolescents

Table D.4Applicability for included studies, KQ2

Author, Year	Population	Intervention	Comparator	Outcome	Setting
Abbasi, 2011¹⁰⁴	N/A	Co-intervention that are likely to modify the effectiveness of therapy	N/A	N/A	N/A
Abikoff, 2004¹⁰⁷	More complex patients than typical of the community	N/A	N/A	N/A	Level of care different from that in the community
Abikoff, 2007¹⁰⁹	Narrow eligibility criteria	Dosing not reflective of current practice	N/A	Short-term follow-up	N/A
Abikoff, 2009¹⁰⁸	More complex patients than typical of the community	N/A	N/A	Other issues	N/A
Abikoff, 2013¹⁰⁶	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Abikoff, 2015¹¹⁰	N/A	N/A	N/A	N/A	N/A
Aevi Genomic Medicine, 2016¹¹³	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Aevi Genomic Medicine, 2018¹¹⁴	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Akhondzadeh, 2004¹¹⁶	N/A	As recommended or commonly used in practice	N/A	N/A	N/A
Allen, 2005¹¹⁸	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Amiri, 2008¹²²	N/A	N/A	N/A	N/A	N/A
Antshel, 2003¹²³	N/A	N/A	N/A	N/A	N/A
Arnold, 2022¹²⁶	N/A	Unclear	N/A	N/A	N/A
Arnold, 2007¹²⁵	N/A	N/A	N/A	N/A	N/A
Ashkenasi, 2011¹²⁷	N/A	N/A	N/A	N/A	N/A
Aviv, 2021¹²⁸	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Azami, 2023¹²⁹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Bakhshayesh, 2011¹³⁰	N/A	N/A	N/A	N/A	N/A
Banaschewski, 2013¹³¹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Bangs, 2007¹³²	N/A	N/A	N/A	N/A	N/A
Bangs, 2008¹³³	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Baziar, 2019¹³⁶	N/A	N/A	N/A	N/A	N/A
Bedard, 2015¹³⁷	N/A	N/A	N/A	N/A	N/A
Behdani, 2013¹³⁸	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Benzing, 2019¹³⁹	N/A	N/A	N/A	N/A	N/A
Biederman, 2005¹⁴⁷	N/A	N/A	N/A	N/A	N/A
Biederman, 2006¹⁴⁶	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Biederman, 2007¹⁴⁴	N/A	N/A	N/A	N/A	N/A
Biederman, 2008¹⁴⁵	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Bigorra, 2016¹⁴⁸	N/A	N/A	N/A	N/A	N/A
Bikic, 2018⁵⁶	N/A	N/A	N/A	N/A	N/A
Bilici, 2004¹⁴⁹	N/A	N/A	N/A	N/A	N/A
Binesh, 2020¹⁵⁰	N/A	N/A	N/A	Unclear	N/A
Blader, 2021¹⁵¹	Narrow eligibility criteria	Co-intervention that are likely to modify the effectiveness of therapy	Comparator unclear	Short-term follow-up	Unclear
Block, 2009¹⁵⁴	N/A	N/A	N/A	N/A	N/A
Blumer, 2009¹⁵⁵	N/A	N/A	N/A	N/A	N/A
Bluschke, 2022¹⁵⁶	DSM-4/5 diagnosis unclear	Co-intervention that are likely to modify the effectiveness of therapy	Unclear	N/A	N/A
Bostic, 2000¹⁵⁸	N/A	N/A	N/A	Short-term follow-up	N/A
Boyer, 2016¹⁶⁰	N/A	N/A	N/A	N/A	N/A
Brams, 2018¹⁶¹	N/A	N/A	N/A	Short-term follow-up	N/A
Breaux, 2018¹⁶³	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Buitelaar, 1996¹⁶⁵	N/A	N/A	N/A	N/A	N/A
Buitelaar, 2007¹⁶⁴	N/A	N/A	N/A	N/A	N/A
Bul, 2016¹⁶⁶	N/A	N/A	N/A	N/A	Unclear
Carucci, 2022¹⁷¹	N/A	N/A	N/A	N/A	N/A
Ceresoli-Borroni, 2021¹⁷⁴	N/A	N/A	N/A	N/A	N/A
Cetin, 2015¹⁷⁵	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Chacko, 2009¹⁷⁶	N/A	N/A	N/A	N/A	N/A
Chang, 2019¹⁷⁸	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Chang, 2022¹⁸⁰	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Childress, 2009¹⁹⁵	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Childress, 2022¹⁹⁴	N/A	N/A	N/A	N/A	N/A
Cho, 2011¹⁹⁶	N/A	Unclear	N/A	Short-term follow-up	N/A
Chu, 2021¹⁹⁹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Churchill, 2018²⁰⁰	N/A	Highly selected intervention team or level of training/proficiency not widely available	Comparator unclear	N/A	N/A
Coelho, 2017²⁰¹	N/A	N/A	N/A	N/A	N/A
Coghill, 2014²⁰²	N/A	N/A	N/A	N/A	N/A
Coles, 2020²⁰⁴	N/A	N/A	N/A	N/A	N/A
Concordia Pharm., 2011²⁰⁵	N/A	Unclear	N/A	N/A	N/A
Conners, 1996²⁰⁶	N/A	Unclear	N/A	Other issues	N/A
Connor, 2010²⁰⁷	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Corkum, 2019²⁰⁸	DSM-4/5 diagnosis unclear	Co-intervention that are likely to modify the effectiveness of therapy	Unclear	Short-term follow-up	N/A
Cornu, 2018²⁰⁹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Crippa, 2019²¹²	N/A	N/A	N/A	N/A	N/A
Dashbozorgi, 2021²¹⁵	Narrow eligibility criteria	N/A	N/A	Short-term follow-up	N/A
David, 2021²¹⁶	N/A	N/A	N/A	N/A	N/A
Daviss, 2008²¹⁷	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Dehbozorghi, 2019²¹⁹	Narrow eligibility criteria	Co-intervention that are likely to modify the effectiveness of therapy	N/A	Short-term follow-up	N/A
Dell’Agnello, 2009²²⁰	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Denton, 2020²²¹	More complex patients than typical of the community	Co-intervention that are likely to modify the effectiveness of therapy	Unclear	Unclear	N/A
Dentz, 2020²²²	More complex patients than typical of the community	Co-intervention that are likely to modify the effectiveness of therapy	N/A	N/A	N/A
Diamond, 1999²²⁴	DSM-4/5 diagnosis unclear	As recommended or commonly used in practice	N/A	Other issues	N/A
Dittmann, 2011²²⁶	N/A	N/A	N/A	N/A	N/A
Dittmann, 2013²²⁵	N/A	N/A	Comparator unclear	N/A	N/A
Dong, 2022²²⁷	N/A	Unclear	N/A	N/A	N/A
Dose, 2017²²⁸	N/A	N/A	N/A	N/A	Level of care different from that in the community
Dovis, 2015²²⁹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Dreakhshanpour, 2022²³²	N/A	N/A	N/A	N/A	N/A
Duke University, 2009²³⁵	N/A	Dosing not reflective of current practice	N/A	Other issues	N/A
Duke University, 2009b²³⁶	N/A	Dosing not reflective of current practice	N/A	Other issues	N/A
DuPaul, 2021²³⁸	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Durgut, 2020²³⁹	N/A	Unclear	N/A	Unclear	N/A
Duric, 2017²⁴⁰	DSM-4/5 diagnosis unclear	Co-intervention that are likely to modify the effectiveness of therapy	N/A	Short-term follow-up	N/A
Egeland, 2013²⁴³	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Eli Lilly, 2004²⁴⁷	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Eli Lilly, 2006²⁴⁸	N/A	N/A	N/A	N/A	N/A
Eli Lilly²⁴⁹	N/A	N/A	N/A	N/A	N/A
Elmaadawi, 2022²⁵²	N/A	Highly selected intervention team or level of training/proficiency not widely available	N/A	Other issues	N/A
Enns, 2017²⁵⁴	N/A	Unclear	Unclear	Other issues	N/A
Epstein, 2007²⁵⁶	N/A	Unclear	N/A	N/A	N/A
Epstein, 2016²⁵⁵	N/A	N/A	N/A	N/A	N/A
Ercan, 2014²⁵⁷	More complex patients than typical of the community	Co-intervention that are likely to modify the effectiveness of therapy	N/A	N/A	N/A
Estrada-Plana, 2019²⁵⁸	N/A	N/A	N/A	Short-term follow-up	Level of care different from that in the community
Evans, 2016²⁵⁹	N/A	N/A	N/A	N/A	N/A
Fabiano, 2016²⁶¹	N/A	N/A	N/A	Other issues	N/A
Fallah, 2018²⁶²	More complex patients than typical of the community	N/A	N/A	Unclear	N/A
Farmer, 2017²⁶⁴	N/A	N/A	N/A	N/A	N/A
Ferrin, 2014²⁶⁵	N/A	N/A	N/A	N/A	N/A
Ferrin, 2020²⁶⁶	N/A	N/A	N/A	N/A	N/A
Findling, 2001²⁷¹	N/A	Dosing not reflective of current practice	N/A	N/A	N/A
Findling, 2008²⁷³	N/A	N/A	N/A	N/A	N/A
Findling, 2010²⁷²	Narrow eligibility criteria	As recommended or commonly used in practice	N/A	N/A	N/A
Findling, 2011²⁷⁰	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Findling, 2019²⁶⁹	N/A	N/A	N/A	N/A	N/A
Florida International University, 2015²⁷⁵	More complex patients than typical of the community	N/A	N/A	Other issues	N/A
Frei, 2001²⁷⁹	N/A	Highly selected intervention team or level of training/proficiency not widely available	Inadequate comparison therapy or use of a substandard alternative therapy	Other issues	N/A
Frei, 2005²⁷⁸	Run-in period with high exclusion rate	N/A	N/A	N/A	N/A
Fuchs, 2003²⁸⁰	N/A	N/A	N/A	N/A	N/A
Fuentes, 2013²⁸¹	N/A	Co-intervention that are likely to modify the effectiveness of therapy	N/A	N/A	N/A
Gard, 2014²⁸⁶	N/A	As recommended or commonly used in practice	N/A	N/A	N/A
Gau, 2006²⁸⁹	Narrow eligibility criteria	N/A	Unclear	N/A	N/A
Gau, 2007²⁸⁸	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Geissler, 2020²⁹⁰	N/A	N/A	N/A	N/A	N/A
Gelade, 2017²⁹¹	N/A	N/A	N/A	N/A	N/A
Geller, 2007²⁹²	N/A	N/A	N/A	Short-term follow-up	Level of care different from that in the community
Gevensleben, 2010²⁹⁴	N/A	N/A	N/A	N/A	N/A
Ghajar, 2018²⁹⁵	Narrow eligibility criteria	N/A	N/A	Short-term follow-up	N/A
Ghanizadeh, 2015²⁹⁶	N/A	Dosing not reflective of current practice	N/A	N/A	N/A
Gonzalez-Castro, 2016³⁰²	N/A	N/A	N/A	Other issues	N/A
Greenhill, 2006³⁰⁵	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Greenhill, 2006³⁰⁴	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Griffiths, 2018³⁰⁶	N/A	N/A	N/A	N/A	N/A
Guevara, 2021³⁰⁸	DSM-4/5 diagnosis unclear	N/A	N/A	N/A	N/A
Gustafsson, 2010³¹⁰	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Hahn-Markowitz, 2020³¹³	N/A	N/A	N/A	N/A	N/A
Harfterkamp, 2012³¹⁷	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Hariri, 2012³¹⁸	DSM-4/5 diagnosis unclear	Co-intervention that are likely to modify the effectiveness of therapy	N/A	Unclear	N/A
Hasslinger, 2021³²⁰	N/A	N/A	N/A	N/A	N/A
Hazell, 2003³²¹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Hemamy, 2021³²⁴	N/A	Dosing not reflective of current practice	N/A	Short-term follow-up	N/A
Herbert, 2013³²⁵	Unclear	Unclear	Unclear	N/A	N/A
Hervas, 2014³²⁶	DSM-4/5 diagnosis unclear	Dosing not reflective of current practice	Inadequate comparison therapy or use of a substandard alternative therapy	Short-term follow-up	N/A
Hirayama, 2014³²⁸	N/A	N/A	N/A	N/A	N/A
Hiscock, 2019³²⁹	N/A	N/A	N/A	N/A	N/A
Hogue, 2020³³⁰	DSM-4/5 diagnosis unclear	Highly selected intervention team or level of training/proficiency not widely available	N/A	Other issues	N/A
Hong, 2016³³²	N/A	Unclear	Unclear	Unclear	N/A
Hosainzadeh Maleki, 2014³³³	N/A	N/A	N/A	N/A	N/A
Huang, 2015³³⁵	N/A	N/A	N/A	N/A	N/A
Huang, 2021³³⁴	N/A	N/A	Comparator unclear	N/A	N/A
Ichikawa, 2020³³⁷	N/A	N/A	N/A	N/A	N/A
Jain, 2011³⁴¹	N/A	N/A	N/A	N/A	N/A
Jensen, 2007³⁴³	Unclear	N/A	N/A	N/A	N/A
Ji, 2023³⁴⁵	Narrow eligibility criteria	N/A	N/A	Other issues	N/A
Johnson, 2009³⁴⁹	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Johnson, 2020³⁴⁸	N/A	N/A	N/A	N/A	N/A
Johnstone, 2022³⁵⁰	N/A	N/A	N/A	N/A	N/A
Kadri, 2019³⁵³	DSM-4/5 diagnosis unclear	N/A	N/A	N/A	N/A
Kahbazi, 2009³⁵⁴	N/A	N/A	N/A	N/A	N/A
Karakaya, 2019³⁵⁷	N/A	N/A	N/A	N/A	N/A
Kareem, 2021³⁵⁸	DSM-4/5 diagnosis unclear	N/A	N/A	Other issues	N/A
Katz, 2010³⁶⁰	N/A	N/A	N/A	Unclear	N/A
Kelsey, 2004³⁶¹	N/A	N/A	N/A	N/A	N/A
Khaksarian, 2021³⁶³	N/A	N/A	N/A	N/A	N/A
Khoshbakht, 2021³⁶⁴	N/A	N/A	N/A	N/A	N/A
Kim, 2022³⁶⁷	Narrow eligibility criteria	N/A	Comparator unclear	N/A	N/A
Kofler, 2020³⁶⁸	N/A	N/A	N/A	N/A	N/A
Kolko, 2020³⁷¹	Unclear	N/A	Comparator unclear	N/A	N/A
Kollins, 2011³⁷⁴	N/A	N/A	N/A	N/A	N/A
Kollins, 2011³⁷³	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Kollins, 2020³⁷²	Narrow eligibility criteria	N/A	N/A	Short-term follow-up	N/A
Korfmacher, 2022³⁷⁵	Narrow eligibility criteria	Co-intervention that are likely to modify the effectiveness of therapy	N/A	N/A	N/A
Kratochvil, 2002³⁷⁶	N/A	N/A	N/A	N/A	N/A
Kratochvil, 2005³⁷⁷	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Kratochvil, 2011³⁷⁸	N/A	N/A	N/A	N/A	N/A
Kurowski, 2019³⁸³	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Lange, 2018³⁸⁴	Narrow eligibility criteria	Highly selected intervention team or level of training/proficiency not widely available	Inadequate comparison therapy or use of a substandard alternative therapy	Short-term follow-up	Unclear
Lavigne, 2011³⁸⁶	N/A	N/A	N/A	N/A	N/A
Law, 1999³⁸⁷	Unclear	As recommended or commonly used in practice	N/A	Other issues	N/A
Li, 2022³⁹²	Narrow eligibility criteria	Unclear	N/A	N/A	N/A
Liang, 2022³⁹⁶	N/A	N/A	N/A	N/A	N/A
Lilly, 2008²⁵⁰	N/A	N/A	Unclear	N/A	N/A
Lim, 2019³⁹⁸	N/A	N/A	N/A	N/A	N/A
Lin, 2014³⁹⁹	N/A	N/A	N/A	Short-term follow-up	N/A
Ludyga, 2022⁴⁰⁶	N/A	Highly selected intervention team or level of training/proficiency not widely available	N/A	Other issues	N/A
Luo, 2022⁴⁰⁹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Lv, 2023⁴¹⁰	Narrow eligibility criteria	Co-intervention that are likely to modify the effectiveness of therapy	Comparator unclear	N/A	N/A
Manor, 2012⁴¹¹	Narrow eligibility criteria	N/A	N/A	Unclear	N/A
Martenyi, 2010⁴¹⁴	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Matthijssen, 2019⁴¹⁸	N/A	N/A	N/A	N/A	N/A
Mattingly, 2020⁴¹⁹	N/A	N/A	N/A	Short-term follow-up	N/A
McCracken, 2016⁴²⁵	N/A	N/A	Comparator unclear	Short-term follow-up	N/A
McGrath, 2011⁴²⁶	N/A	N/A	N/A	Unclear	N/A
Mehri, 2020⁴²⁸	More complex patients than typical of the community	N/A	N/A	Unclear	N/A
Meyer, 2021⁴³⁰	N/A	N/A	N/A	N/A	N/A
Michelson, 2001⁴³²	N/A	N/A	N/A	N/A	N/A
Michelson, 2002⁴³¹	N/A	N/A	N/A	N/A	N/A
Mikami, 2013⁴³³	More complex patients than typical of the community	Highly selected intervention team or level of training/proficiency not widely available	N/A	Other issues	N/A
Minder, 2018⁴³⁵	N/A	N/A	N/A	N/A	N/A
Mohammadi, 2010⁴³⁹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Mohammadi, 2012⁴⁴⁰	N/A	N/A	N/A	N/A	N/A
Mohammadzadeh, 2019⁴⁴¹	N/A	N/A	N/A	N/A	N/A
Montoya, 2009⁴⁴²	N/A	N/A	N/A	N/A	N/A
Morell, 2019⁵⁰⁴	N/A	N/A	N/A	N/A	N/A
Mostajeran, 2020⁴⁴³	N/A	N/A	N/A	N/A	N/A
Motaharifard, 2019⁴⁴⁴	Narrow eligibility criteria	As recommended or commonly used in practice	Comparator unclear	Short-term follow-up	Unclear
Mount Sinai, 2012⁵³⁹	DSM-4/5 diagnosis unclear	N/A	N/A	Short-term follow-up	N/A
Myers, 2015⁴⁵¹	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Nasser, 2020⁴⁵³	N/A	N/A	N/A	N/A	N/A
Nasser, 2021⁴⁵⁴	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Nasser, 2021⁴⁵⁵	N/A	N/A	N/A	N/A	N/A
Nasser, 2021⁴⁵²	N/A	N/A	N/A	N/A	N/A
Nejati, 2021⁴⁵⁶	N/A	Unclear	N/A	N/A	N/A
Nejati, 2022⁴⁵⁷	N/A	N/A	N/A	N/A	N/A
Newcorn, 2005⁴⁶¹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Newcorn, 2008⁴⁶⁰	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Newcorn, 2016⁴⁵⁹	N/A	N/A	N/A	N/A	N/A
NF Coll. Group, 2021⁴⁵⁸	N/A	N/A	N/A	N/A	N/A
Oppenheimer, 2019⁴⁶⁶	N/A	N/A	Comparator unclear	Short-term follow-up	N/A
Pelham, 2016⁴⁷¹	N/A	Co-intervention that are likely to modify the effectiveness of therapy	N/A	N/A	N/A
Pelsser, 2011⁴⁷²	Run-in period with high exclusion rate	Highly selected intervention team or level of training/proficiency not widely available	N/A	N/A	N/A
Perez-Alvarez, 2009⁴⁷⁴	Narrow eligibility criteria	N/A	N/A	Other issues	N/A
Pfiffner, 2014⁴⁷⁶	N/A	N/A	N/A	N/A	N/A
Pongpitakdamrong, 2021⁴⁷⁸	N/A	N/A	N/A	N/A	N/A
Power, 2012⁴⁸⁰	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Prasad, 2007⁴⁸¹	N/A	N/A	N/A	N/A	N/A
Purper-Ouakil, 2021⁴⁸³	N/A	Highly selected intervention team or level of training/proficiency not widely available	N/A	N/A	N/A
Qian, 2018⁴⁸⁴	N/A	N/A	N/A	N/A	N/A
Qian, 2021⁴⁸⁵	Narrow eligibility criteria	Highly selected intervention team or level of training/proficiency not widely available	Unclear	N/A	Level of care different from that in the community
Rafeiy-Torghabeh, 2021⁴⁸⁸	N/A	N/A	N/A	N/A	Unclear
Raghuveer, 2020⁴⁸⁹	N/A	Unclear	N/A	N/A	N/A
Rahmani, 2022⁴⁹⁰	N/A	N/A	N/A	N/A	N/A
Rajabi, 2020⁴⁹²	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Riggs, 2011⁴⁹⁷	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Rothe, 2023⁵⁰³	More complex patients than typical of the community	Co-intervention that are likely to modify monitoring strategies	N/A	Other issues	N/A
Rucklidge, 2018⁵⁰⁵	N/A	N/A	N/A	N/A	N/A
Saito, 2020⁵⁰⁷	N/A	N/A	N/A	N/A	N/A
Salardini, 2016⁵⁰⁸	N/A	N/A	N/A	Short-term follow-up	N/A
Salehi, 2010⁵⁰⁹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Salehi, 2016⁵¹⁰	Narrow eligibility criteria	N/A	N/A	Other issues	N/A
Sallee, 2009⁵¹¹	N/A	N/A	N/A	N/A	N/A
Sangal, 2006⁵¹²	N/A	N/A	N/A	N/A	N/A
Sangal, 2014⁵¹³	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Schertz, 2022⁵¹⁷	N/A	Unclear	N/A	N/A	N/A
Schorr-Sapir, 2021⁵²⁰	N/A	Highly selected intervention team or level of training/proficiency not widely available	N/A	N/A	N/A
Schramm, 2016⁵²¹	N/A	N/A	N/A	N/A	N/A
Schuck, 2018⁵²²	N/A	N/A	N/A	N/A	N/A
Sciberras, 2020⁵²³	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Seattle Children’s Hospital, 2015¹⁹³	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Shang, 2020⁵²⁵	N/A	N/A	N/A	Unclear	N/A
Shaywitz, 2017⁵²⁶	More complex patients than typical of the community	As recommended or commonly used in practice	N/A	N/A	Unclear
Shen, 2021⁵²⁹	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Shuai, 2020⁵³⁰	Narrow eligibility criteria	N/A	N/A	Short-term follow-up	N/A
Sibley, 2016⁵³³	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Sibley, 2018⁵³¹	N/A	N/A	N/A	N/A	N/A
Sibley, 2020⁵³⁴	N/A	N/A	Comparator unclear	N/A	N/A
Sibley, 2021⁵³²	N/A	N/A	N/A	N/A	N/A
Siebelink, 2021⁵³⁵	N/A	N/A	N/A	N/A	N/A
Simonoff, 2013⁵³⁸	DSM-4/5 diagnosis unclear	N/A	N/A	Short-term follow-up	N/A
Singer, 1995⁵⁴⁰	N/A	N/A	N/A	N/A	N/A
Smit, 2021⁵⁴⁴	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Sonuga-Barke, 2001⁵⁵⁰	N/A	N/A	N/A	N/A	Level of care different from that in the community
Sonuga-Barke, 2004⁵⁵¹	DSM-4/5 diagnosis unclear	N/A	N/A	Unclear	N/A
Sonuga-Barke, 2018⁵⁵²	N/A	N/A	N/A	N/A	N/A
Spencer, 2002⁵⁵⁴	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Spencer, 2002⁵⁵⁵	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Spencer, 2006⁵⁵⁷	N/A	N/A	N/A	N/A	N/A
Spencer, 2008⁵⁵⁶	N/A	N/A	Comparator unclear	Short-term follow-up	N/A
Sprich, 2016⁵⁶⁰	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Steele, 2006⁵⁶¹	Narrow eligibility criteria	As recommended or commonly used in practice	N/A	N/A	N/A
Steiner, 2014⁵⁶²	N/A	N/A	N/A	N/A	N/A
Storebo, 2012⁵⁶⁵	N/A	N/A	N/A	N/A	N/A
Strehl, 2017⁵⁶⁷	N/A	N/A	N/A	N/A	Level of care different from that in the community
Su, 2016⁵⁶⁸	N/A	N/A	N/A	N/A	N/A
Sugaya 2022⁵⁶⁹	N/A	N/A	N/A	N/A	N/A
Supernus Pharmaceuticals, 2016⁵⁷²	More complex patients than typical of the community	Unclear	N/A	N/A	N/A
Svanborg, 2009⁵⁷³	N/A	N/A	Comparator unclear	N/A	N/A
Swanson, 2006⁵⁷⁴	N/A	N/A	N/A	N/A	N/A
Takahashi, 2009⁵⁷⁵	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Tamm, 2013⁵⁷⁸	N/A	N/A	N/A	N/A	N/A
Tamm, 2017⁵⁷⁷	More complex patients than typical of the community	N/A	N/A	N/A	N/A
Tan, 2016⁵⁷⁹	N/A	N/A	N/A	N/A	N/A
Tiwawatpakorn, 2021⁵⁸⁵	DSM-4/5 diagnosis unclear	N/A	N/A	N/A	N/A
Trebaticka, 2006⁵⁸⁶	Unclear	N/A	N/A	Other issues	N/A
Tris Pharma, 2014⁵⁸⁸	Unclear	Unclear	Unclear	Unclear	Unclear
TS Study Group, 2002³⁸⁰	N/A	N/A	N/A	N/A	N/A
TS Study Group, 2002b³⁸¹	N/A	N/A	N/A	N/A	N/A
Tutty, 2003⁵⁸⁹	N/A	N/A	N/A	N/A	N/A
Tzang, 2016⁵⁹⁰	Narrow eligibility criteria	As recommended or commonly used in practice	N/A	Short-term follow-up	N/A
Vaidyanathan, 2023⁵⁹³	N/A	Co-intervention that are likely to modify the effectiveness of therapy	N/A	N/A	N/A
Valero, 2021⁵⁹⁴	N/A	N/A	N/A	N/A	N/A
van der Donk, 2015⁵⁹⁵	More complex patients than typical of the community	N/A	N/A	N/A	Unclear
Van der Heijden, 2007⁵⁹⁶	More complex patients than typical of the community	As recommended or commonly used in practice	N/A	N/A	N/A
van der Oord, 2007⁵⁹⁷	More complex patients than typical of the community	N/A	N/A	N/A	N/A
van Stralen, 2020⁵⁹⁸	N/A	N/A	N/A	N/A	N/A
Voigt, 2001⁶⁰¹	Narrow eligibility criteria	N/A	N/A	Other issues	N/A
Volpe, 2009⁶⁰²	More complex patients than typical of the community	N/A	N/A	Unclear	N/A
Wang, 2007⁶⁰⁴	N/A	Dosing not reflective of current practice	N/A	N/A	N/A
Weber, 2008⁶⁰⁶	N/A	N/A	N/A	N/A	N/A
Wehmeier, 2012⁶⁰⁸	N/A	N/A	N/A	N/A	N/A
Weiss, 2005⁶¹¹	N/A	N/A	N/A	Short-term follow-up	Unclear
Weiss, 2007⁶¹⁰	N/A	N/A	N/A	N/A	N/A
Weiss, 2021⁶¹²	N/A	N/A	N/A	Short-term follow-up	N/A
Wennberg, 2018⁶¹³	Unclear	Highly selected intervention team or level of training/proficiency not widely available	N/A	N/A	Unclear
Wietecha, 2009⁶¹⁶	Narrow eligibility criteria	N/A	Unclear	N/A	N/A
Wigal, 2004⁶¹⁷	N/A	N/A	N/A	N/A	N/A
Wigal, 2011⁶¹⁸	N/A	N/A	N/A	N/A	N/A
Wilens, 2005⁶²¹	N/A	N/A	N/A	Short-term follow-up	N/A
Wilens, 2008⁶¹⁹	N/A	N/A	N/A	N/A	N/A
Wilens, 2011¹⁰⁵	N/A	N/A	N/A	N/A	Unclear
Wilens, 2012⁶²²	N/A	N/A	N/A	N/A	N/A
Wilens, 2015⁶²³	Narrow eligibility criteria	As recommended or commonly used in practice	N/A	N/A	N/A
Wilkes-Gillan, 2016⁶²⁴	More complex patients than typical of the community	N/A	N/A	Unclear	N/A
Willens, 2011⁶²⁰	Narrow eligibility criteria	As recommended or commonly used in practice	N/A	Unclear	Level of care different from that in the community
Wolraich, 2001⁶²⁶	N/A	N/A	N/A	N/A	N/A
Wu, 2023⁶²⁸	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Young, 2014⁶³⁴	Narrow eligibility criteria	Dosing not reflective of current practice	Inadequate comparison therapy or use of a substandard alternative therapy	N/A	Unclear
Zarinara, 2010⁶³⁶	N/A	N/A	N/A	N/A	N/A
Zavadenko, 2019⁶³⁷	N/A	N/A	Unclear	Unclear	Unclear
Zheng, 2020⁶⁴⁰	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Zhu, 2017⁶⁴⁵	N/A	N/A	N/A	N/A	Unclear
Zhu, 2022⁶⁴³	Narrow eligibility criteria	N/A	N/A	N/A	N/A
Zhuo, 2022⁶⁴⁶	Narrow eligibility criteria	Unclear	N/A	N/A	N/A

From: Appendix D, Critical Appraisal and Applicability Tables

Cover of ADHD Diagnosis and Treatment in Children and Adolescents

ADHD Diagnosis and Treatment in Children and Adolescents [Internet].

Comparative Effectiveness Review, No. 267.

Peterson BS, Trampush J, Maglione M, et al.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2024 Mar.

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