Table 7Summary of Findings by Comparison — IV Acetaminophen Versus Placebo

Citation Study design Outcome Outcome results Effect estimate

(95% CI)

P value
IV acetaminophen Placebo
Yin et al. (2022)13aSR with meta-analysis (1 relevant RCTa)Total morphine consumption within 24-hours postsurgery in mg, mean (SD)5.53 (4.49)7.85 (4.17)MD = –2.32

(–4.69 to 0.05)

—
Aksoy et al. (2023)15RCTTotal morphine consumption, mean (SD)10.64 (3.53)16.04 (3.99)—< 0.05

CI = confidence interval; MD = mean difference; RCT = randomized controlled trial; SD = standard deviation; SR = systematic review.

a

Findings reported from results of the 1 relevant RCT by Shimia and colleagues (2014).16

From: Opioid-Sparing Effects of IV Acetaminophen for Patients Undergoing Surgery

Cover of Opioid-Sparing Effects of IV Acetaminophen for Patients Undergoing Surgery
Opioid-Sparing Effects of IV Acetaminophen for Patients Undergoing Surgery: Rapid Review [Internet].
Santos C, Lachance CC, Bailey S; Authors.
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