Table 2Characteristics of the Included Systematic Review

Study citation, country, funding Study designs and numbers of primary studies included Population characteristics Relevant intervention and comparator(s) Relevant outcome measure, length of follow up
Yin et al. (2022)13

China

Funding: NR.

 Systematic review and meta-analysis of RCTs reporting the effectiveness and safety of IV paracetamol for reducing opioid consumption in lumbar disc surgery.

Literature searched until October 2021, with an update before submission for publication.

5 RCTs included in the SR with 1 relevant RCTa

Individuals undergoing lumbar disc surgery.

N = 271 (n = 52 for relevant RCT).

Intervention: Peri-operative administration of IV paracetamol

Comparator: Placebo

Outcome: Total morphine consumption in mg (primary outcome)

Length of follow up: 24-hours postsurgery

NR = not reported; RCT = randomized controlled trial.

a

Study by Shimia and colleagues (2014).16

From: Opioid-Sparing Effects of IV Acetaminophen for Patients Undergoing Surgery

Cover of Opioid-Sparing Effects of IV Acetaminophen for Patients Undergoing Surgery
Opioid-Sparing Effects of IV Acetaminophen for Patients Undergoing Surgery: Rapid Review [Internet].
Santos C, Lachance CC, Bailey S; Authors.
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