Table 2. [Select Features of Okur-Chung Neurodevelopmental Syndrome]. - GeneReviews®

Feature	Proportion of Persons w/Feature	Comment
Developmental delay / intellectual disability	35/35 ¹	Generally mild-to-moderate, w/language development most affected domain
Dysmorphic facial features	29/36	Round face & short, broad nasal tip
Behavioral issues	27/36
Hypotonia	22/36	Generally mild
Brain MRI abnormalities	11/20 ²	Nonspecific
Musculoskeletal findings	15/36	Kyphoscoliosis, loose joints, hernia
Difficulty feeding	14/36	From infancy to childhood
Postnatal short stature	14/36	Generally 2-3 SD below mean
Difficulty gaining weight	13/36
Sleep issues	13/36	Disrupted circadian rhythm
Microcephaly / smaller head (absolute or relative)	12/36
Seizures	11/36	No specific type
Ataxia / gait difficulties / poor coordination	9/36

From: Okur-Chung Neurodevelopmental Syndrome

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Adam MP, Feldman J, Mirzaa GM, et al., editors.

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