Table 2.

Periodontal Ehlers-Danlos Syndrome: Frequency of Select Features

Feature% of Persons
with Feature		Comment
DentalSevere early-onset periodontitis99%Diagnosed in childhood or adolescence (mean onset age 14 yrs)
Receding gums98% of adults
Generalized lack of attached gingiva93%Identification requires clinical expertise; appears to be pathognomonic for pEDS but not assessed/reported in all persons w/pEDS.
Easy bruising96%Mainly on the shins, but also in unusual areas (e.g., cheeks & thighs)
Pretibial plaques83%Also reported as pretibial (hemosiderin) discolorations
Skin fragility, atrophic scarring, delayed wound healing50%
Joint hypermobility44%Previously reported as mainly affecting the small joints
Arterial aneurysms/dissections8/145Abdominal aorta (n=2), carotid artery (2), cerebral artery (3), unknown location (1)
Brain white matter abnormality8/8Reported in all adults who had a brain MRI
Organ rupture2/145Lung, diaphragm, intestine, small bowel, eardrum

From: Periodontal Ehlers-Danlos Syndrome

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