Table 5. [Recommended Surveillance for Individuals with Tangier Disease]. - GeneReviews®

System/Concern	Evaluation	Frequency
Histiocytic	Assessment for hepatosplenomegaly by physical exam & abdominal imaging modalities	At each visit
Neurologic	Neurologic eval	Annually
Ophthalmologic	Ophthalmologic eval
Cardiovascular	Cardiovascular risk assessment, incl noninvasive assessment of atherosclerotic plaque burden ¹	Annually beginning in early adulthood
Hematologic	Complete blood count w/differential	As clinically indicated

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