| Time After Starting | Time After Stopping | ALT (U/L) | Alk P (U/L) | Bilirubin (mg/dL) | Other |
|---|---|---|---|---|---|
| Pre | Pre | 109 | 712 | 2.3 | Ursodiol 1.2 g/d |
| Pre | 91 | 664 | 2.7 | |
| 0 | Pre | Obeticholic acid started (5 mg daily) | |||
| 2 weeks | Pre | 46 | 431 | 2.2 | Itching |
| 1 month | Pre | 50 | 372 | 2.2 | |
| 2 months | Pre | 52 | 382 | 2.6 | |
| 3 months | 0 | 79 | 519 | 7.6 | OCA stopped |
| 9 days | 53 | 551 | 6.4 | Ascites noted | |
| 4 months | 30 days | 51 | 651 | 6.2 | EGD: Varices |
| 5 months | 50 days | 83 | 959 | 4.2 | INR 1.1 |
| 6 months | 80 days | 76 | 865 | 3.9 | Lactulose started |
| 9 months | 6 months | 89 | 743 | 2.7 | |
| 11 months | 8 months | 69 | 445 | 2.6 | Itching resolved |
| 14 months | 11 months | 52 | 362 | 2.4 | Ascites resolved |
| Normal Values | <35 | <130 | <1.2 | ||
From: Obeticholic Acid
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