CHOLESTATIC HEPATITIS

Image Allopurinol-Image001.jpg Allopurinol may cause cholestatic hepatitis. This case shows canalicular (arrow) and hepatocellular cholestasis in zone 3. Only very mild inflammation is present in this photo. The central vein (V) is indicated.
Image Allopurinol-Image002.jpg In this case, there was mild portal inflammation, mainly composed of lymphocytes. In over half the portal areas, no duct could be found, consistent with a vanishing bile duct syndrome. This portal area only shows an artery (A) and vein (V).

From: Allopurinol

Cover of LiverTox
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet].

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