 | Zone 3 necrosis. The hepatocytes around the vein (V) have been lost and replaced by an inflammatory infiltrate composed of lymphocytes and plasma cells. |
 | In this portal area there is a dense inflammatory infiltrate composed of lymphocytes, plasma cells and scattered eosinophils. There is marked interface hepatitis. |
 | Confluent bridging necrosis extending between two portal areas and involving zone 3. The bile ducts (arrows) and hepatic vein (V) mark the involved structures. Interface hepatitis is present around the edge of the residual hepatocyte parenchyma. |
From: Diclofenac
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