Medication:Ibuprofen (600 mg daily)
Pattern:Initially mixed (R=4.5), later cholestatic (R=<1.0)
Severity:4+ (jaundice, hospitalization, progressive hepatic failure)
Latency:3 weeks
Recovery:No. Jaundice and vanishing bile duct syndrome one year later
Other medications:Allergy injections for six weeks before onset

From: Ibuprofen

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LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet].
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