Table 5.

Recommended Surveillance for Individuals with Hereditary Distal Renal Tubular Acidosis

System/
Concern		EvaluationComment
Renal Venous blood gas
  • In rapidly growing persons (infants & young children): at least every 3-4 mos once blood pH is normalized w/o evidence of respiratory compensation; in older children & adults: at least every 6 mos
  • Sample to be drawn in fasting conditions & immediately before scheduled dose of alkali
Serum creatinine, urea, sodium, potassium, chloride, calcium, phosphate, alkaline phosphatase, albumin
  • In rapidly growing persons (infants & young children), at least every 3-4 mos once adequate control is achieved
  • In older children & adults, at least every 6 mos
Urinalysis, urine creatinine, sodium, potassium, calcium, citrateAnnually; more frequently when adjusting treatment
Renal ultrasoundAnnual eval for nephrocalcinosis, urolithiasis, & cysts in asymptomatic persons
ENT AudiometryAnnual eval for hearing loss
Skeletal Bone densitometryNo consensus exists on benefit of follow-up bone densitometry.
Constitutional Measure length/height, & weight; calculate BMIIn infants, at least every 3 mos; in older children, at least every 6 mos until achievement of final height

BMI = body mass index; ENT = ear, nose, and throat

From: Hereditary Distal Renal Tubular Acidosis

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