Table 8. [Recommended Surveillance for Individuals with FARS2 Deficiency: Later-Onset Spastic Paraplegia]. - GeneReviews®

System/Concern	Evaluation	Frequency
Musculoskeletal	PT/OT eval; assessment for contractures, scoliosis, & foot deformities; consider need for positioning &/or mobility devices.	Each visit
Neurologic	Monitor those w/seizures as clinically indicated.	If concerns for new seizure activity or progression of seizures; seizures are usually brief & resolve over time
Assess for new manifestations such as myoclonus, tremor, bradykinesia, dystonia, dysarthria.	Each visit
Development	Monitor developmental progress & educational needs.	If concern for developmental delay / learning difficulties

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