Table 4.

Treatment of Manifestations in Individuals with GRIN2B-Related Neurodevelopmental Disorder

Manifestation/ConcernTreatmentConsiderations/Other
Abnormal vision &/or strabismus Standard treatment(s) as recommended by experienced ophthalmologist
Seizures Standard treatment w/ASM by experienced neurologist 1Many ASMs may be effective; none has been demonstrated effective specifically for this disorder.
Hypotonia, spasticity, & movement disorder Standard treatment(s) as recommended by experienced neurologist

ASM = anti-seizure medication

1.

Education of parents regarding common seizure presentations is appropriate. For information on non-medical interventions and coping strategies for parents or caregivers of children diagnosed with epilepsy, see Epilepsy Foundation Toolbox.

From: GRIN2B-Related Neurodevelopmental Disorder

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