Table 2.

MPPH Syndrome: Frequency of Select Features

Feature% of Persons w/FeatureComment
Megalencephaly100%
Cortical malformations100%Typically BPP but other types of PMG have also been seen
Hydrocephalus~50%Ventriculomegaly seen in most individuals
Oromotor dysfunction~50%Specifically assoc w/BPP
Hypotonia~80%
Epilepsy~100%
Intellectual disability100%
Postaxial polydactyly50%

BPP = bilateral perisylvian polymicrogyria; PMG = polymicrogyria

From: MPPH Syndrome

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