Table 6.

MAPT-Related Frontotemporal Dementia: Recommended Surveillance

System/ConcernEvaluationFrequency
Neurologic Neurologic exam for new manifestations &/or response to medicationsAt each visit
Mobility / Activities of daily living Physical medicine & rehab / PT & OTPer treating clinician
Cognitive function Rapid screening tools, incl tests of verbal fluencyAt each visit
Psychiatric/behavioral manifestations Medical history, neurologic exam
Dysarthria Eval by speech-language pathologistPer treating clinician
Dysphagia Medical historyAt each visit
Sialorrhea
Bladder function
Family/caregiver support/resources Assess family need for social work support (e.g., palliative/respite care, home nursing, other local resources), care coordination, or follow-up genetic counseling if new questions arise (e.g., family planning).

From: MAPT-Related Frontotemporal Dementia

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