Table 3. [Clinical Features of DBH Deficiency]. - GeneReviews®

Feature	# of Individuals ¹
Severe orthostatic hypotension	21/21 (100%)
Anemia	9/15 (60%)
Ptosis of eyelids	12/14 (86%)
Hyperflexible or hypermobile joints	6/10 (60%)
EKG abnormalities ²	2/12 (17%)
Epileptiform symptoms	4/12 (33%)
Nasal stuffiness	10/10 (100%)
Hypoglycemia	4/12 (33%)
Sluggish deep-tendon reflexes	3/9 (33%)
Increased plasma creatinine	6/11 (54%)
Polyuria/nocturia	3/9 (33%)
High palate	9/10 (90%)
Increased BUN	6/9 (67%)
Muscle hypotonia	3/9 (33%)
Postprandial hypotension	3/7 (43%)
Sleep irregularities	5/7 (71%)
Impaired ejaculation	4/4 (100%)

From: Dopamine Beta-Hydroxylase Deficiency

GeneReviews^® [Internet].

Adam MP, Feldman J, Mirzaa GM, et al., editors.

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