Table 6.

Greig Cephalopolysyndactyly Syndrome: Treatment of Manifestations

Manifestation/
Concern
TreatmentConsiderations/Other
Polydactyly Surgical repair
  • Undertaken on an elective basis
  • Preaxial polydactyly of the hands is considered higher priority for surgical correction than postaxial polydactyly of the hand or any type of polydactyly of the foot due to importance of early & proper development of prehensile grasp.
  • As for any malformation of the feet, surgical correction must be carefully considered; cosmetic benefits & easier fitting of shoes can be outweighed by potential orthopedic complication.
Cutaneous
syndactyly
Surgical repairUndertaken if syndactyly is more than minimal
Seizures ASM therapy as needed

ASM = anti-seizure medication

From: Greig Cephalopolysyndactyly Syndrome

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