Table 8.

Hemoglobin Analysis in Alpha-Thalassemia Trait and Alpha-Thalassemia Silent Carriers

Hemoglobin TypeNormalα-Thalassemia Trait 1 (--/αα or -α/-α)α-Thalassemia Silent Carrier 2 (-α/αα)
HbA 96%-98%96%-98%96%-98%
HbF <1%<1.0%<1.0%
HbH 000
HbA2 2%-3%1.5%-3.0%2%-3%
Hb Bart 000
Hb Portland 000
1.

Deletion or inactivation of two α-globin genes either in cis configuration (--/αα) or in trans configuration (-α/-α)

2.

Deletion or inactivation of one α-globin gene (-α/αα)

From: Alpha-Thalassemia

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