Table 3.

Nutritional Phases in Prader-Willi Syndrome

PhaseMedian AgesClinical Characteristics
0 Prenatal to birth↓ fetal movements & lower birth weight than sibs
1a Birth to 9 mosHypotonia w/difficulty feeding & ↓ appetite
1b 9 to 25 mosImproved feeding & appetite; growing appropriately
2a 2.1 to 4.5 yrsWeight ↑ w/o appetite ↑ or excess calories
2b 4.5 to 8 yrs↑ appetite & calories but can feel full
3 8 yrs to adulthoodHyperphagic, rarely feels full
4 AdulthoodAppetite no longer insatiable for some

Adapted from Miller et al [2011]

From: Prader-Willi Syndrome

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