Table 2. [Thiamine-Responsive Megaloblastic Anemia Syndrome: Frequency of Select Features]. - GeneReviews®

Feature	% of Persons w/Feature	Comment
Megaloblastic anemia	60%-70%	Anemia is present in >90% of persons.
Progressive sensorineural deafness	>90%
Non-type I diabetes mellitus	>90%
Ophthalmologic manifestations	20%-30%	Incl optic atrophy
Cardiovascular abnormalities	20%-30%
Neurologic manifestations	20%-40%
Thrombocytopenia	10%-30%

From: Thiamine-Responsive Megaloblastic Anemia Syndrome

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Adam MP, Feldman J, Mirzaa GM, et al., editors.

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