Allele nameOther name(s)HGVS reference sequencedbSNP reference identifier for allele location
CodingProtein
HLA-B*58​:01 Not applicable*Not applicable*Not applicable*
*

For the MHC region, variations in genes such as HLA-B occur across the whole sequence of the gene, not a single locus. Therefore, the HLA-B*58:01 allele is defined by its sequence (GenBank: EU499350.1) rather than single coding or protein variants.

Guidelines for the description and nomenclature of gene variations are available from the Human Genome Variation Society (HGVS): http://www​.hgvs.org/content/guidelines

Guidelines on nomenclature of the HLA system are available from HLA Nomenclature: http://hla​.alleles.org/

MHC, major histocompatibility complex

From: Allopurinol Therapy and HLA-B*58:01 Genotype

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Medical Genetics Summaries [Internet].
Pratt VM, Scott SA, Pirmohamed M, et al., editors.
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