Table 4. [Recommended Surveillance for Individuals with X-Linked Protoporphyria]. - GeneReviews®

System/Concern	Evaluation	Frequency
Erythrocyte protoporphyrin levels & plasma total porphyrins	Both free & zinc-chelated	Annually
Anemia	Complete blood count w/indices
Iron store depletion	Serum ferritin levels
Hepatic involvement	Hepatic function (liver transaminases)
US exam (if cholelithiasis is suspected)	As indicated
Fibroscan^® to evaluate for hepatic fibrosis
Vitamin D deficiency	Vitamin D 25-OH levels whether or not receiving supplements	Annually

GeneReviews^® [Internet].

Adam MP, Feldman J, Mirzaa GM, et al., editors.

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