Table 6.

Recommended Evaluations Following Initial Diagnosis in Individuals with Malignant Hyperthermia Susceptibility

System/ConcernEvaluation
MH acute episode
  • Arterial blood gas analysis
  • Measurement of serum electrolytes (Na, K, Cl)
  • Lactate
  • Measurement of serum CK concentrations until normalized
  • Coagulation studies (INR, PTT, D-dimer)
  • Urine myoglobin
  • Serum myoglobin concentration
  • Liver function tests (AST, ALT, alkaline phosphatase, bilirubin)
  • Continuous core temperature monitoring until episode resolves
Neuromuscular Neurologic assessment for evidence of muscle damage
Other Consultation w/clinical geneticist &/or genetic counselor

From: Malignant Hyperthermia Susceptibility

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