Table 2. [Select Features of the 16p11.2 Recurrent Deletion]. - GeneReviews®

Feature	% of Persons w/Feature	Comment
Developmental delay	Most (if not all)	Degree varies significantly.
Psychiatric/behavioral issues	>90%	50% have ≥1 psychiatric/behavioral diagnoses. Most report symptoms of behavioral conditions.
Motor speech disorders	80%	Incl apraxia, dysarthria; majority mild-to-moderate, some minimally verbal
Language disorder	80%-90%	Broadly impaired receptive, expressive, pragmatic domains
Obesity	75%	Onset in early adolescence through adulthood
Motor coordination difficulties	60%
Autistic features / autism	20%-25%
Seizures	25%
Vertebral anomalies	21%	May be assoc w/scoliosis
Hearing loss	<11%	Both sensorineural & conductive reported
Paroxysmal kinesigenic dyskinesia (PKD)	≤9%	Incl benign familial infantile seizures, PKD, & PKD w/infantile convulsions
Cardiac malformations	6%

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