Table 6.

Recommended Surveillance for Individuals with Pseudoxanthoma Elasticum (PXE)

System/ConcernEvaluationFrequency
Skin Consultation w/cosmetic dermatologist or reconstructive surgeon if redundant skin presents risk of infectionPer patient
Eye Retinal exam by retinal specialistAnnually or more frequently per treating ophthalmologist when retinal neovascularization is active &/or treatment is ongoing
Patient use of Amsler grid to monitor for central visual disturbancesDaily
Gastrointestinal Per treating gastroenterologistPer treating gastroenterologist
Vascular Claudication of leg
&/or arm muscles 		Per treating vascular clinic/surgeonPer treating vascular clinic/surgeon
Stroke Per treating stroke clinic/neurologistPer treating stroke clinic/neurologist
Renovascular
hypertension 		Per treating nephrologistPer treating nephrologist
Cardiovascular complications
angina, MI) 		Per treating cardiologistPer treating cardiologist

MI = myocardial infarction

From: Pseudoxanthoma Elasticum

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