Table 4. [Recommended Surveillance for Individuals with Holt-Oram Syndrome]. - GeneReviews®

System/Concern	Evaluation	Frequency
Cardiac	EKG	Annually in those at risk of developing a conduction defect
EKG combined w/Holter monitor	Annually in those w/known conduction disease to assess progression
Echocardiogram	Every 1-5 yrs; may be recommended by managing cardiologist depending on nature & significance of potential septal defects.

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