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| Status |
Public on May 03, 2024 |
| Title |
Effect of DLBCL-associated NOTCH2 mutants on genomic RBP-J localization and H3K27 acetylation |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Assessment of the genome-wide effect of DLBCL-asscociated NOTCH2 mutants in DLBCL on RBPJ and H3K27acetylation. DLBCL cell lines U2932 cells stably expressing HA-tagged NOTCH2(WT), NOTCH2(R2400*) or NOTCH2(Q2140*) were subjected to chromatin immnunoprecipitation DNA-sequencing (ChIP-seq) for RBP-J and H3K27ac.
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| Overall design |
ChIP-seq analysis or RBP-J and H3K27ac in U2932 cells stably expressing HA-tagged NOTCH2(WT), NOTCH2(R2400*) or NOTCH2(Q2140*)
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| Contributor(s) |
Busino L, Zhou N, Liu Y, Li Q, Wan L |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
May 03, 2023 |
| Last update date |
May 03, 2024 |
| Contact name |
Luca Busino |
| E-mail(s) |
businol@upenn.edu
|
| Organization name |
Luca Busino
|
| Department |
Cancer Biology
|
| Street address |
421 Curie Blvd, 705 BRB II/III
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
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| Platforms (1) |
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| Samples (7)
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| This SubSeries is part of SuperSeries: |
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| Relations |
| BioProject |
PRJNA967020 |
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