Table 4.4Age at onset of constipation or diagnosis in children with Hirschsprung's disease and children with idiopathic constipation

StudyAge at onset of constipation or diagnosis
Lewis et al., 2003aHDAge of onset of constipation
Mean8 months (range 1 day to 9 years)
First week of life60%
First month of life70%
First year of life87%
After 1 year of life13%
ICAge of onset of constipation
Mean15 months (range 7 days to 16 years)
First week of life15%
First month of life55%
First year of life68%
After 1 year of life32%
Pini-Prato et al., 2007HDAge of onset of constipation
At <1 year (n=47)96%
At >1 year (n=47)4%
ICAge of onset of constipation
At <1 year (n=45)80%
At >1 year (n=45)20%
Khan et al., 2003HDMean age of patients diagnosed with HD: 3.64 months (range 2 days to 4 years)
ICUnclear
Gosh et al., 1998HDAge at diagnosis: 1 day to 3 years
<4 weeksn=14
4 to 12 weeksn=1
12 weeks to 1 yearn=1
>1 yearn=1
Age of onset of constipation
< 4 weeksn=17
ICAge at biopsy: 1 day to 13 years
< 4 weeksn=20
4 to 12 weeksn=12
12 weeks to 1 yearn=14
>1 yearn=78
Age of onset of constipation
<4 weeksn=40
4 to 12 weeksn=32
12 weeks to 1 yearn=22
>1 yearn=25
a

Data available for 46 patients with HD and 40 patients with IC

HD: Hirschsprung's disease, C: constipation, y: year

From: 4, Clinical investigations

Cover of Constipation in Children and Young People
Constipation in Children and Young People: Diagnosis and Management of Idiopathic Childhood Constipation in Primary and Secondary Care.
NICE Clinical Guidelines, No. 99.
National Collaborating Centre for Women's and Children's Health (UK).
London: RCOG Press; 2010.
Copyright © 2010, National Collaborating Centre for Women's and Children's Health.

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