Monocyte-derived dendritic cells from young and aged donors
Summary:
Comparison of dendritic cells (DCs) from young (20 to 27 years) and aged (77 to 87 years) donors. DCs are antigen-presenting cells important in initiating and regulating innate and adaptive immune responses. Results provide insight into the molecular basis of the decline in DC function with age.
GPL571:
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Citation:
Cao JN, Agrawal A, Sharman E, Jia Z et al. Alterations in gene array patterns in dendritic cells from aged humans. PLoS One 2014;9(9):e106471. PMID: 25191744
