HIV and tuberculosis co-infection: peripheral blood mononuclear cell
Summary:
Analysis of PBMCs from HIV patients with and without M. tuberculosis (TB) co-infection. Co-infection with TB is a cause of death in HIV-infected individuals. Results provide insight into a molecular signature to distinguish HIV/TB co-infected patients from HIV mono-infected patients.
Dawany N, Showe LC, Kossenkov AV, Chang C et al. Identification of a 251 gene expression signature that can accurately detect M. tuberculosis in patients with and without HIV co-infection. PLoS One 2014;9(2):e89925. PMID: 24587128