Analysis of Saccharomyces cerevisiae cells subjected to anti-malaria drug quinine (QN) at concentration that exerted a very slight effect on cellular growth. Results provide insight into the molecular mechanisms underlying QN action and the host response to the drug.
dos Santos SC, Tenreiro S, Palma M, Becker J et al. Transcriptomic profiling of the Saccharomyces cerevisiae response to quinine reveals a glucose limitation response attributable to drug-induced inhibition of glucose uptake. Antimicrob Agents Chemother 2009 Dec;53(12):5213-23. PMID: 19805573
