Clotiazepam is not approved for marketing in the United States by the U.S. Food and Drug Administration. Very little information is available on the passage of clotiazepam into milk. One review recommends avoiding clotiazepam during breastfeeding.[1] An alternate drug is preferred, especially while nursing a newborn or preterm infant. If clotiazepam is used, monitor the infant for sedation, poor feeding and poor weight gain.