No information is available on the clinical use of perflutren during breastfeeding. Because of the extremely short elimination half-life of perflutren (<2 minutes) from the body, use of perflutren either as albumin microspheres or lipid microspheres is acceptable in nursing mothers.[1] Because of the lack of information, the American College of Radiology states that temporary (~24 hours) pumping and discarding of milk may be considered.[2] However, this recommendation appears to be excessively cautious.