No information is available on the clinical use of diethyltoluamide (DEET) during breastfeeding. However, the Centers for Disease Control and Prevention and U.S. Environmental Protection Agency consider DEET to be safe and effective during breastfeeding when used as directed.[1] It should be used by breastfeeding women to avoid exposure to mosquito-borne viruses.[1-3] Avoid application directly to the nipple and other areas where the infant might directly ingest the product.