Genome sequence of the human- and animal-pathogenic strain Nocardia cyriacigeorgica GUH-2

Anthony Zoropogui; Petar Pujic; Philippe Normand; Valérie Barbe; Blaine Beaman; LoVelle Beaman; Patrick Boiron; Céline Colinon; Amélie Deredjian; Arnault Graindorge; Sophie Mangenot; Sylvie Nazaret; Manuelle Neto; Stéphanie Petit; David Roche; David Vallenet; Veronica Rodríguez-Nava; Yves Richard; Benoit Cournoyer; Didier Blaha

doi:10.1128/JB.00161-12

Genome sequence of the human- and animal-pathogenic strain Nocardia cyriacigeorgica GUH-2

J Bacteriol. 2012 Apr;194(8):2098-9. doi: 10.1128/JB.00161-12.

Affiliation

¹ Université de Lyon, Research Group on Bacterial Opportunistic Pathogens and Environment, Biological Resource Center, UMR5557 Ecologie Microbienne, CNRS, VetAgro Sup Veterinary Campus, Lyon, France.

Abstract

The pathogenic strain Nocardia cyriacigeorgica GUH-2 was isolated from a fatal human nocardiosis case, and its genome was sequenced. The complete genomic sequence of this strain contains 6,194,645 bp, an average G+C content of 68.37%, and no plasmids. We also identified several protein-coding genes to which N. cyriacigeorgica's virulence can potentially be attributed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Gene Expression Regulation, Bacterial
Genome, Bacterial*
Humans
Molecular Sequence Data
Nocardia / classification*
Nocardia / genetics*
Nocardia Infections / microbiology*

Associated data

GENBANK/FO082843