Multidrug and broad-spectrum cephalosporin resistance among Salmonella enterica serotype enteritidis clinical isolates in southern Italy

J Clin Microbiol. 2002 Jul;40(7):2662-5. doi: 10.1128/JCM.40.7.2662-2665.2002.

Abstract

From 1992 to 1997, only six sporadic isolates of Salmonella enterica serotype Enteritidis from patients with cases of gastroenteritis in southern Italy exhibited resistance to broad-spectrum cephalosporins. Five isolates produced SHV-12, and one isolate encoded a class C beta-lactamase. The bla(SHV-12) gene was located in at least two different self-transferable plasmids, one of which also carried a novel class 1 integron.

MeSH terms

  • Base Sequence
  • Cephalosporin Resistance
  • Cross Infection / drug therapy
  • Cross Infection / microbiology
  • Drug Resistance, Multiple, Bacterial
  • Gastroenteritis / drug therapy
  • Gastroenteritis / microbiology
  • Genes, Bacterial
  • Humans
  • Italy
  • Plasmids / genetics
  • Salmonella Infections / drug therapy
  • Salmonella Infections / microbiology
  • Salmonella enteritidis / drug effects*
  • Salmonella enteritidis / enzymology
  • Salmonella enteritidis / genetics
  • Salmonella enteritidis / isolation & purification*
  • beta-Lactamases / classification
  • beta-Lactamases / genetics

Substances

  • beta-lactamase SHV-12
  • beta-Lactamases